Detection of cbs gene polymorphism and its relation to homocysteine level in vitiligo / (Record no. 54308)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02920cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160106s2015 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.10.M.Sc.2015.Sh.D |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sherin Mohamed Shafik Elgohary |
| 245 10 - TITLE STATEMENT | |
| Title | Detection of cbs gene polymorphism and its relation to homocysteine level in vitiligo / |
| Statement of responsibility, etc. | Sherin Mohamed Shafik Elgohary ; Supervised Samar Mohamed Ragaie Eltahlawi , Dalia Mohamed Abdelhalim , Olfat Jamil Shaker |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تحديد تعدد اشكال جين سيستا ثيونين بى سنثيتاز و علاقته بمستوى هرمون الهوموسيستايين فى مرض نقص الصبغة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Sherin Mohamed Shafik Elgohary , |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 165 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Patients and methods: This observastional case control study was conducted on 100 patients with vitiligo and 80 age and sex matched controls. From each A 5ml blood sample was taken for detection of CBS (844ins68) gene polymorphism by PCR and detection of Hcy level by Axis Homocysteine Enzyme Immunoassay kit. Results: A significant higher frequency of the CBS (844ins68) gene polymorphism (homozygous or heterozygous) was found in the patient group in relation to the control group (25% vs 12.5% with P = 0.035*). A statistically significant difference was found between cases with normal genotype and those with mutant genotype as regards family history (p = 0.000*). Also a statistically significant difference was found between cases and controls as regards Hcy level (p = 0.000*). However no statistically significant difference was found between cases with normal genotype and those with mutant genotype as regards the age (P = 0.506.), extent (P = 0.655), age of onset (P = 0.097), duration of illness (P = 0.179), VIDA (P = 0.412),VASI (p = 0.905) and Hcy level (p = 0.403). A significant correlation was found between Hcy level and age of patients, disease duration, extent of disease and VASI score p (0.033), (0.021) , (0.000), (.000) respectively. Non significant correlation was found between Hcy level and CBS (844ins68) genotypes and VIDA (p = 0.232), (p = 0.103) respectively. Conclusion: We concluded that CBS gene polymorphism may paly an additional role in the susceptibility of individuals for vitiligo |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cystathionine -Ý- synthase |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Polymorphism |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Vitiligo |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dalia Mohamed Abdelhalim , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Olfat Jamil Shaker , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Samar Mohamed Ragaie Eltahlawi , |
| Relator term | |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Enas |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.10.M.Sc.2015.Sh.D | 01010110067380000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.10.M.Sc.2015.Sh.D | 01020110067380000 | 22.09.2023 | CD - Rom | 67380.CD |