Study of the role of brain-derived neurotrophic factor (BDNF) val66met genetic polymorphism and serum BDNF in the phenotypic expression of mood disorders in a sample of Egyptian patients / (Record no. 54352)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03197cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031405.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160110s2015 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.21.Ph.D.2015.Di.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Dina Badie Taher Kattaria |
| 245 10 - TITLE STATEMENT | |
| Title | Study of the role of brain-derived neurotrophic factor (BDNF) val66met genetic polymorphism and serum BDNF in the phenotypic expression of mood disorders in a sample of Egyptian patients / |
| Statement of responsibility, etc. | Dina Badie Taher Kattaria ; Supervised Lamis Ali Elray , Mona Yehia Rakhawy , Mohamed Nasreldin Sadek |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | فى الأنماط الظاهرية لأمراض اضطرابات المزاج فى عينة من المرضى المصريين (BDNF) و المستوى المصلى للعامل المغذى العصبي الناتج في المخ (VAL66MET) دراسة دور التعدد الجينى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Dina Badie Taher Kattaria , |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 286 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Neuro Psychiatry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: There is substantial evidence that Brain Derived Neurotrophic Factor is involved in the aetiology of mood disorders, however genetic studies assessing the relationship between BDNF and these disorders have produced conflicting results Aim of the study: to investigate the association of BDNF Val66Met polymorphism and serum BDNF with mood disorders per se as well with specific phenotypic aspects in these disorders in a sample of Egyptian patients Methods: A case control study including 62 patients with the diagnoses of bipolar and major depression disorders and 31 controls. The two groups of patients were assessed clinically and were subjected to Hamilton Depression Rating scale, Young Mania Rating scale and Child Traumatic Questionnaire, in addition to the neurocognitive and personality assessment which were administrated to all participants. Serum BDNF levels were determined by using ELISA and Genotyping of Val66Met polymorphism by Real Time Polymerase Chain Reaction(PCR) Results: The serum BDNF level in the control group was found higher than both groups of patients, and this difference was statistically significant between the bipolar group and the control group as well as between the bipolar and the major depression groups of patients .No statistical significant difference between the 3 groups regarding the three genotypes of the Val 66 Polymorphism, but there was a statistical significant difference concerning the relation between the risky genotypes in both groups of patients and certain clinical aspects and some of the Wisconsin indices of the WCST |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | BDNF-Serum |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Bipolar |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Polymorphism |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lamis Ali Elray , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Nasreldin Sadek , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mona Yehia Rakhawy , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Enas |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.21.Ph.D.2015.Di.S | 01010110067384000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.21.Ph.D.2015.Di.S | 01020110067384000 | 22.09.2023 | CD - Rom | 67384.CD |