MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02752cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
160117s2015 ua f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.19.04.Ph.D.2015.Mo.M |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohamed Elsayed Mostafa Gad Elmola |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Micro RNA as a prognostic factor in stage II colorectal cancer patients / |
| Statement of responsibility, etc. |
Mohamed Elsayed Mostafa Gad Elmola ; Supervised Nasr Mohamed Ali Allahlobi , Abeer Ahmed Bahanassy , Ola Mohamed Reda Khorshid |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
متناهية الصغر كعامل مساعد على التنبؤ بالمستقبل المرضى لمرضى المرحلة الثانية من سرطان القولون و المستقيم RNA جزيئات الـ |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Mohamed Elsayed Mostafa Gad Elmola , |
| Date of publication, distribution, etc. |
2015 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
225 P. ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology - Medical |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Patients with stage II CRC have a varying survival outcomes, Therefore, it is critical to identify new prognostic and predictive biomarkers that can help to identify more aggressive disease forms among stage II patients and to individualize therapy accordingly. MicroRNAs (miRNAs) are small, noncoding, single stranded RNAs that regulate gene expression post transcriptionally. Present findings have indicated that miRNAs are differently expressed in normal and neoplastic colon tissues and they can distinguish CRC tumors according to histopathologic, prognostic, and predictive characteristics. The aim of this prospective study was to identify the potential prognostic value of five suggested miRNAs, namely; miR 21, miR 498, miR 137, miR - 145 and miR 320, in patients with stage II CRC. Also, this study assessed the concordance between tissue and blood miRNAs. This study included 124 patients with stage II CRC who attended the NCI Medical Oncology clinics during the period from January 2004 to December 2014. All patients included in the study received treatment and were followed - up in the NCI during the last 10 years. The expression levels of the five studied miRNAs were examined by qRT PCR analysis. Additionally, blood samples were drawn from 41 patients recruited in the study in the last 3 years of recruitment to assess the level of miRNAs in blood |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
MicroRNAs |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Prognosis |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Stage II CRC |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Abeer Ahmed Bahanassy , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Nasr Mohamed Ali Allahlobi , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ola Mohamed Reda Khorshid , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Samia |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
