MARC details
000 -LEADER |
fixed length control field |
02568cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
160118s2015 ua d f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.08.09.M.Sc.2015.Ab.E |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Abeer Ali Ebrahim Elnaggar |
245 10 - TITLE STATEMENT |
Title |
Effect of an insulin sensitizer agent, lipid lowering agent and an antioxidant on non - alcoholic fatty liver in rats / |
Statement of responsibility, etc. |
Abeer Ali Ebrahim Elnaggar ; Supervised Hekma Abdellatif , Afaf A. Ain Shoka , Fatma Abdellatif Ebeid |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
تأثير عامل مخفض للدهون و عامل محفز للأنسولين بدون أو مصاحب لعامل مضاد للأكسدة على الكبد الدهنى الغير كحولى فى الجرذان |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Abeer Ali Ebrahim Elnaggar , |
Date of publication, distribution, etc. |
2015 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
179 P. : |
Other physical details |
charts ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology |
520 ## - SUMMARY, ETC. |
Summary, etc. |
The prevalence of non - alcoholic fatty liver disease (NAFLD) has markedly increased, especially with patient exhibit one or more features of the metabolic syndrome. This study investigates the effect of rosuvastatin (RSV), pioglitazone (PGZ) or/and Ý-carotene (ÝC) in NAFLD - induced rats. Rats were classified into 13 groups; normal (I), NAFLD - induced with high - fat diet (HFD; II), NAFLD switched to regular diet (RD; III), NAFLD - HFD or NAFLD - RD treated with RSV (IV, V), PGZ (VI,VII), ÝC (VIII, IX) RSV + ÝC (X, XI) and PGZ + ÝC (XII,XIII). respectively for 4 wk (weeks 13 - 16) and then killed to obtain serum samples and liver tissues. Liver histology, lipid profile, liver oxidative stress markers, and adipocytokines were measured. Liver sections of NAFLD - HFD rats revealed steatosis, loss of hepatic architectecture, inflammation and hepatocyte vacuolation with high percentage of cell fibrosis. Serum levels of ALT, AST, ALP, GGT and lipid profile (triglycerides, cholesterol, LDL and VLDL) was significantly increased (P < 0.05) compared with normal group. Also, hepatic MDA level and serum NASH biomarkers; leptin, TNF - Ü and TGF-Ý1 were furthermore increased |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
NAFLD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Pioglitazone |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Rosuvastatin |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Afaf Ain Shoka , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Fatma Abdellatif Ebeid , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Hekma Abdellatif , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Samia |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |