Possible protective effect of NanoChitosan and Quercetin against oxidative stress in experimentally-induced liver toxicity in rats / (Record no. 55365)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02688cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031436.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160306s2015 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.09.M.Sc.2015.Ra.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Raghda Hamed Abdallah Saleh |
| 245 10 - TITLE STATEMENT | |
| Title | Possible protective effect of NanoChitosan and Quercetin against oxidative stress in experimentally-induced liver toxicity in rats / |
| Statement of responsibility, etc. | Raghda Hamed Abdallah Saleh ; Supervised Ezz Eldin S. Eldenshary , Mosaad A. Abdelwahhab |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | التأثير الوقائي المحتمل للنانوكيتوزان و الكويرستين ضد الكرب التأكسدي الناتج عن التسمم الكبدي التجريبي في الجرذان |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Raghda Hamed Abdallah Saleh , |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 222 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacologyand Toxicology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The present study was primarily designed to investigate the hepatoprotective effect of nanochitosan (NC) alone or in combination with quercetin (Q) against CCl₄ -induced hepatotoxicity in animal model. 4 Accordingly, adult female albino rats were treated for 3 weeks after being randomly assigned into 12 groups including the control group, the group treated with CCl twice a week (1.0 ml/kg b.w), the group treated with the low 4 dose of NC (NC-LD) (140 mg/kg/day), the group which received the high dose of NC (NC-HD) (280 mg/kg/day), the group that received Q (50 mg/kg/day), the groups treated with Q plus NC-LD, Q plus NC-HD, and the groups treated with CCl₄ plus Q and/or NC at the two tested doses. At the end of the treatment 4 period, blood and tissue samples were collected for serum biochemical and antioxidant enzymes analysis, oxidative stress markers, histological examination and genotoxicity evaluation. The results revealed that animals which received CCl showed a significant increase in AST, ALT, ALP, AFP, CEA and the level of lipid peroxidation measured as (MDA). In addition to a significant decrease in TP, albumin, GPx, CAT and SOD accompanied with severe histological changes in the liver and kidney tissues |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Liver |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Nanochitosan |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Quercetin |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ezz Eldin Saeed Eldenshary , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mosaad Attya Abdelwahhab , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Soheir |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.09.M.Sc.2015.Ra.P | 01010110068179000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.09.M.Sc.2015.Ra.P | 01020110068179000 | 22.09.2023 | CD - Rom | 68179.CD |