Interleukin 17-A as an inflammatory marker of multiple organ dysfunction syndrome in patients with major trauma : (Record no. 55718)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02781cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031446.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160324s2015 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.07.M.Sc.2015.Em.I |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Emily Samir Mikhael Georgy |
| 245 10 - TITLE STATEMENT | |
| Title | Interleukin 17-A as an inflammatory marker of multiple organ dysfunction syndrome in patients with major trauma : |
| Remainder of title | Prospective observational study / |
| Statement of responsibility, etc. | Emily Samir Mikhael Georgy ; Supervised Lamia Mansour , Riham Elessawy , Riham Elsayed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | إنترلوكين 17- أ كدلالة للالتهاب فى متلازمة الخلل الوظيفي عديد الأعضاء فى مرضى الرضوض الكبرى: |
| Remainder of title | دراسة استطلاعية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Emily Samir Mikhael Georgy , |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 92 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Multiple organ dysfunction syndrome (MODS) is a systemic, dysfunctional inflammatory response characterized with high mortality rate. The Interleukin-17 (IL-17) family is generally regarded as a bridge system connecting innate and adaptive immunity in induction and mediation of pro-inflammatory responses. Aim of work: The aim of the present study is to investigate association between IL- 17 and MODS in polytrauma patients as well as to test the clinical relevance of IL-17 single nucleotide polymorphism (rs1974226) in patients with major trauma. Results: IL-17 serum level was significantly increased (p=0.039) in group I versus group II patients. As for the IL-17 genotyping, the present study revealed no association (p=0.197) between IL-17 rs1974226 different genotypes and the development of MODS. With regards to mortality, IL-17 serum level was significantly higher (p =0.016) in patients who had a lethal outcome versus those who survived. The ROC curve analysis showed that IL-17 can be a promising biomarker in the prediction of MODS (AUC=0.721) in patients with polytrauma. Conclusion: IL-17 can be considered an important early biochemical marker for predicting the development of MODS. On the other hand, IL-17 rs1974226 might not be associated with the occurrence of MODS |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Interleukin-17 |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | MODS |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Polytrauma |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lamia Mansour , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Riham Elessawy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Riham Elsayed , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Soheir |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.07.M.Sc.2015.Em.I | 01010110068319000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.07.M.Sc.2015.Em.I | 01020110068319000 | 22.09.2023 | CD - Rom | 68319.CD |