MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02741cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
160412s2015 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.08.01.M.Sc.2015.Mo.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohamed Rizk Abdelkhalik Rizk |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Possible treatment regimens against the hepatotoxic effect of some antitubercular drugs in rats / |
| Statement of responsibility, etc. |
Mohamed Rizk Abdelkhalik Rizk ; Supervised Samy Abdelfattah Abdelazim , Rokaya Mahmoud Hussein , Ahmed Abdellatif Badr |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
أنظمة علاج محتملة لتخفيف الآثار الكبدية الضارة لبعض الأدوية المستخدمة فى علاج مرضى السل فى الجرذان |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Mohamed Rizk Abdelkhalik Rizk , |
| Date of publication, distribution, etc. |
2015 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
208 P. : |
| Other physical details |
charts , facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Biochemistry |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Aim: Tuberculosis is a dangerous disease and its death toll is increasing year by year. Intake of isoniazid and rifampicin might lead to fatal hepatorenal toxicity. The emerging field of stem cell therapy has raised great hope for improving the treatment of liver diseases. Results: The study revealed that serum liver enzymes activities, liver and kidney thiobarbituric acid reactive substance and nitric oxide levels, serum lipid profile and DNA fragmentation which exhibited by comet assay were significantly increased by isoniazid and rifampicin treatment associated with marked reduction of serum levels of albumin, total protein and albumin/globulin ratio, as well as liver and kidney glutathione levels and antioxidant enzymes activities, catalase and superoxide dismutase, as compared to normal controls. These results showed that N-acetyl cysteine, mesenchymal stem cells and white tea extract exerts their protective activity by different extents on liver and kidney by inhibiting the production of free radicals through induction of antioxidant enzymes and improving non-enzymatic thiol antioxidant, glutathione, and returning back the tested parameters towards near the normal controls. Furthermore, liver and kidney functions were improved greatly by mesenchymal stem cells followed by N- acetyl cysteine and white tea extract, respectively |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Hepatorenal toxicity |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Isoniazid |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Rifampicin |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ahmed Abdellatif Badr , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Rokaya Mahmoud Hussein , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Samy Abdel-Fattah Abdelazim , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Soheir |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
