MARC details
000 -LEADER |
fixed length control field |
02458cam a2200313 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
160418s2015 ua f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.12.10.M.Sc.2015.El.S |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Elmahdi Abubaker Mahmmoud Abubaker |
245 10 - TITLE STATEMENT |
Title |
Synthesis and biological evaluation of some new heterocyclic compounds incorporating pyrrole moiety / |
Statement of responsibility, etc. |
Elmahdi Abubaker Mahmmoud Abubaker ; Supervised Sayed Mohamed Riyadh , Sobhy Mohamed Gomaa |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
تشييد وتقييم النشاط البيولوجى لبعض المركبات غير متجانسة الحلقة الجديدة المحتوية على البترول |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Elmahdi Abubaker Mahmmoud Abubaker , |
Date of publication, distribution, etc. |
2015 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
128 P. ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry |
520 ## - SUMMARY, ETC. |
Summary, etc. |
A novel series of 2-ethylidenehydrazono-4-substituted-5- arylazothiazoles and 3-amino-5-arylazo-2,3-dihydrothiazoles was prepared by cyclocondensation of Ü-keto hydrazonoyl halides with ethylidenethiosemi- carbazide and ethylidenethiocarbohydrazide, respectively. These cyclo- condensation reactions were achieved by using chitosan-grafted-poly- (vinylpyridine) as a novel basic catalyst. Also, reactions of ethylidenethiosemi- carbazide or ethylidenethiocarbohydrazide with N-phenyl benzenecarbo- hydrazonoyl chlorides, bereft of Ü-keto group, using grafted-chitosan, proceeded with similar mechanism and afforded the same 1,3,4-thiadiazoles as the end products. The structures of the newly synthesized compounds were established on the basis of spectroscopic evidences and their alternative synthesis by other methods. Also, the molecular mechanics calculations were used to explain the stability of these stereoselective products. Moreover, the selected newly synthesized products were evaluated for their anti-cancer activity against a colon carcinoma cell line (HCT-116) and liver carcinoma cell line )HepG-2( and the results revealed promising activity |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Incorporating |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
New Heterocyclic Compounds |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Pyrrole Moiety |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Sayed Mohamed Riyadh , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Sobhy Mohamed Gomaa , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Soheir |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |