Study on possible pharmacological effects of gliclazide alone or in combination with carbamazepine or alpha lipoic acid in experimentally induced diabetic neuropathy in rats / (Record no. 56283)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03700cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031503.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160505s2015 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.09.M.Sc.2015.Mo.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Farouk Ahmed Abdelsalam |
| 245 10 - TITLE STATEMENT | |
| Title | Study on possible pharmacological effects of gliclazide alone or in combination with carbamazepine or alpha lipoic acid in experimentally induced diabetic neuropathy in rats / |
| Statement of responsibility, etc. | Mohamed Farouk Ahmed Abdelsalam ; Supervised Ezz-Eldin S. Eldenshary , Rania M. Abdelsalam |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | درا{uئإآ٣}{uئإ٩٤} {uئإأآ}{uئإإ٦} ا{uئإء٣}{uئإ٩٨}{uئإإ٤}{uئإ٨إ}{uئإؤئ}{uئآئئ}{uئإ٩٤} {uئإء٣}{uئإءء}وث {uئإ٩٧}{uئإ٨٤}{uئإ٩آ}{uئآئئ}{uئإءإ}ات {uئإؤ٣}{uئإ٨إ}ر{uئإإ٣}{uئإ٨إ}{uئإؤآ}{uئإإإ}{uئإؤئ}{uئإإإ}{uئإ٩ئ}{uئآئئ}{uئآءآ} {uئإؤئ}{uئإءء}واء {uئإ٩ئ}{uئإإ٠}{uئآئئ}{uئإؤأ}{uئإئأ}زا{uئآئإ}{uئإءء} {uئإإ٣}{uئإإ٨}{uئإؤ٤}{uئإءإ}داً أو {uئإإ٣}{uئإآأ}{uئإء٤}{uئإإإ}{uئإ٩١}{uئإ٨إ} {uئإ٩١}{uئإؤأ}{uئإ٨إ}ر{uئإ٩١}{uئإ٨إ}{uئإإ٣}{uئآئئ}{uئإآ٠}ا{uئإ٩١}{uئآئئ}{uئإإ٦} او {uئإء٣}{uئإإ٤}{uئإآإ} ا{uئإئ٧}{uئإؤئ}{uئإؤ٤}{uئإ٨إ} {uئإؤئ}{uئآئئ}{uئإ٩٢}{uئإإإ}{uئآئإ}{uئإؤء} {uئإؤ٣}{uئإئ٢} ا{uئإؤئ}{uئإء٠}{uئإءإ}ذان ا{uئإؤئ}{uئإإ٤}{uئإآأ}{uئإ٨إ}{uئإ٩١}{uئآءآ} {uئإ٩٧}{uئإء٠}{uئإءإ}{uئآئإ}{uئإ٩٢}{uئآئئ}{uئإ٨إ} {uئإ٩١}{uئإ٨إ}{uئإأآ}{uئإ٩٨}{uئإئأ}ل ا{uئإئ٧}{uئإأآ}{uئإآأ}{uئإ٨إ}ب ا{uئإؤئ}{uئإآ٤}{uئإؤأ}{uئإءإ}ي |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mohamed Farouk Ahmed Abdelsalam , |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 180 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The present study aimed to evaluate the possible pharmacological effects of carbamazepine (CMB) and alpha lipoic acid (ALA) added to an antidiabetic agent, gliclazide (GZ), against experimentally induced diabetic neuropathy in rats. The study was divided into a pilot study and a main study. The pilot study was carried out to determine the time required to develop early diabetic neuropathy in STZ-induced diabetes in male rats. According to the results obtained from the pilot study, the main study was carried out to assess the possible treatment and prophylactic effects of CMB and ALA against the development of diabetic neuropathy after fourteen consecutive days of daily combined treatment with GZ. The assessments were accomplished by: 1- Monitoring behavioral responses to external thermal and mechanical stimuli. 2- Biochemical evaluation for carbohydrate metabolism by determining glucose serum levels and C-peptide, beside inflammatory biomarkers such as TNF alpha serum level and IL-10, oxidative stress biomarkers including serum nitric oxide (NO) level and MDA level, and high affinity insulin receptor (HAIR) and low affinity insulin receptor (LAIR) levels in hippocampus tissue |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hippocampus tissue |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Inflammation |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Oxidative stress |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ezz Eldin S. Eldenshary , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rania M. Abdelsalam , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Aml |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.09.M.Sc.2015.Mo.S | 01010110068786000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.09.M.Sc.2015.Mo.S | 01020110068786000 | 22.09.2023 | CD - Rom | 68786.CD |