Clinicopathological studies on some gold nanoparticles and their effects on some viral diseases / (Record no. 56706)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02816cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031516.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160529s2015 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.10.05.Ph.D.2015.Mo.C |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mostafa Ahmed Mostafa Aly Elgaffary |
| 245 10 - TITLE STATEMENT | |
| Title | Clinicopathological studies on some gold nanoparticles and their effects on some viral diseases / |
| Statement of responsibility, etc. | Mostafa Ahmed Mostafa Aly Elgaffary ; Supervised Mostafa M. Bashandy , Alaa R. Ahmed , Iman K. Ahmed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسات باثولوجية إكلينيكية على جسيمات الذهب النانوية وتأثيراتها على بعض الأمراض الفيروسية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mostafa Ahmed Mostafa Aly Elgaffary , |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 138 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Clinical Pathology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Viruses belonging to the Flaviviridae family cause clinically significant diseases in humans and animals. This family includes three genera: Pestivirus [including bovine viral diarrhea virus (BVDV)], Flavivirus [including yellow fever virus (YFV), dengue virus, and West Nile virus (WNV)], and Hepacivirus [including hepatitis C virus (HCV)]. BVDV is responsible for major losses in cattle, causing a range of clinical manifestations. BVDV is considered to be a valuable surrogate virus model for identifying and characterizing antiviral agents to be used against HCV. In some aspects of viral replication, BVDV is more advantageous than the currently used HCV replicon systems. The purpose of this study was to evaluate the in- vitro and in-vivo cytotoxic effect and antiviral properties of Thiol-peglated gold nanoparticles. Evaluation of the cytotoxicity of prepared gold nanoparticles did not show toxic effects to maden derby bovine kidney (MDBK) cells with concentration of 2 and 4 ppm. Afterward the antiviral activity of nanoparticles was evaluated by the inhibition of the cytopathic effect on infected MDBK cells by means of (MTT) based colorimetric assay and was found that 4 PPM is the optimum conc. for virus inhibition. Then proving of rabbits as laboratory host for BVDV via pathogenicity test, Real-Time PCR and immunohistochemistry was necessary for in-vivo experiment |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | BVDV |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Gold nanoparticles |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Nanotechnology |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Alaa Raffat Ahmed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Iman Kamel Ahmed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mostafa Mahmoud Bashandy , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Aml |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.10.05.Ph.D.2015.Mo.C | 01010110069085000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.10.05.Ph.D.2015.Mo.C | 01020110069085000 | 22.09.2023 | CD - Rom | 69085.CD |