Evaluation of the anti-inflammatory activity of some dietary supplements in chronic inflammation model / (Record no. 56740)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03546cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031517.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160531s2015 ua o f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.07.04.M.Sc.2015.Me.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mervat Hassan Hassan Shehata |
| 245 10 - TITLE STATEMENT | |
| Title | Evaluation of the anti-inflammatory activity of some dietary supplements in chronic inflammation model / |
| Statement of responsibility, etc. | Mervat Hassan Hassan Shehata ; Supervised Samir Abdelmoneim Ahmed , Ebtesam Abdelmoneim Mahmoud , Doha Abdo Mohamed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم التأثير المضاد للألتهابات لبعض المكملات الغذائية فى نموذج التهابات مزمنة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mervat Hassan Hassan Shehata , |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 120 P. : |
| Other physical details | photographs ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Agriculture - Department of Agricultural Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Rheumatoid arthritis is the most common rheumatic disease and emerged as an important worldwide public health problem. The objective of the present research was evaluation of the anti arthritic effect of thyme, turmeric, and cinnamon petroleum ether and ethanol extracts on adjuvant induced arthritis (AIA), which is similar to rheumatoid arthritis in human. The anti arthritic effect and mechanism of action of these extracts have been studied through measuring the size of inflammation and determination of inflammatory and oxidative stress markers. The safety of the studied plants' extracts on liver and kidney functions were evaluated. Total phenolic contents in the plants' powder, Fatty acids and unsaponifiable matter (UNSAP) in the petroleum ether extracts' were determined. Cinnamon showed the highest content of total phenolic compound (5.320 g GAE / 100g sample). GLC investigation of UNSAP revealed that campesterol, stigmasterol and Ý- amyrin were present in all the studied plants. Ý- sitosterol was present only in cinnamon. GLC analysis of the fatty acids showed that linolenic acid ({uF077}-3) was present in thyme, turmeric and cinnamon by 8.721%, 8.488% and 1.797%, respectively. All extracts produced significant reduction in inflammation ranged from 44 to 54%. Ethanol extract of turmeric showed the highest inhibition activity (54%). All studied extracts showed improvement in plasma malondialdehyde (MDA) level as oxidative stress marker and tumor necrosis factor- Ü (TNF- Ü) as inflammatory marker. Plasma levels of total protein, albumin and A / G ratio increased significantly in arthritic rats given daily oral dose of extracts, while plasma globulin reduced significantly. Oral administration of extracts showed significant improvement in nutritional parameters. All spices extracts showed complete safety towards liver and kidney functions. The present study proves the anti inflammatory activity of turmeric, cinnamon and thyme petroleum ether and ethanol extracts, which may have beneficial effects against rheumatoid arthritis onset/progression as shown in AIA rat model |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Adjuvant arthritis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Anti inflammatory |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Phenolic compounds |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Doha Abdo Mohamed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ebtesam Abdelmoneim Mahmoud , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Samir Abdelmoneim Ahmed , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.07.04.M.Sc.2015.Me.E | 01010110069118000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.07.04.M.Sc.2015.Me.E | 01020110069118000 | 22.09.2023 | CD - Rom | 69118.CD |