MARC details
| 000 -LEADER |
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| fixed length control field |
03229cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
160613s2015 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
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| Holding library |
Deposite |
| 097 ## - Thesis Degree |
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| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| Classification number |
Cai01.11.28.M.Sc.2015.Wa.D |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Wasim Farhan Krech |
| 245 10 - TITLE STATEMENT |
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| Title |
Diagnostic value of hepcidin testing among the anemic critically Ill children / |
| Statement of responsibility, etc. |
Wasim Farhan Krech ; Supervised Amina Abdelsalam Mahmoud , Shereen Abdelmonem Mohamed , Ahmed Mohamed Ali Abdelhafez |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
القيمة التشخيصية لاختبار الهيبسيدين في الاطفال المصابين بفقر الدم و الحالات الحرجة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Wasim Farhan Krech , |
| Date of publication, distribution, etc. |
2015 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
90 P. : |
| Other physical details |
charts , facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
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| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Background: Anemia in the critically ill patients is frequent and multifactorial, with the two main contributing factors being inflammation and iron deficiency. Objective: to report the serum hepcidin values among anemic critically- ill children, to investigate the relationship, between serum hepcidin and various clinical and laboratory characteristics and to assess the predictability of iron deficiency in critically ill children by serum hepcidin. Results: The main admitting diagnoses were pneumonia in 32.5%, and bronchopneumonia in 19%. PIM score ranged from 2.4 to 100. Forty-nine (61.25%) had blood transfusion during admission. Low serum iron (mean of 32.9 mg/dl) was seen in 81%, 64%) had elevated serum ferritin, and 4% had low ferritin. Mean serum hepcidin was 2.45 ng/mL with 63.75% of the patients had elevated serum hepcidin above the referral range. Mortality rate was 49%. Children with negative CRP; Group 1 (n=29) and those with positive CRP; Group 2 (n=51) were comparable regarding their age. Group 1 had significantly lower mean Hepcidin (p=0.001) and TIBC (p=0.02), and higher serum iron (p=0.01), when compared to group 2. Hepcidin was found to correlate inversely with hemoglobin (r=-0.2; p=0.05), hematocrit (r=-0.2; p=0.04) and serum iron (r=-0.2; p=0.04) and proportionally with PIM score (r=-0.2; p=0.03), C-reactive protein (r= 0.4, p=0.04) and serum ferritin (r=0.2, p=0.03). ROC curve showed that area under the curve (AUC) of hepcidin was 0.4; (p=0.04). Conclusions& recommendations: Serum hepcidin values were higher than normal in the vast majority of anemic critically-ill children due to acute inflammation. Low serum hepcidin is an indicator of iron deficiency anemia and serum hepcidin levels {u2265}3.11 ng/ml can predict iron deficiency anemia in critically ill children who developed anemia during PICU admission even in the presence of inflammation. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
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| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Anemia |
| 653 #4 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Critical illness |
| 653 #4 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Hepcidin |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Ahmed Mohamed Ali Abdelhafez , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Amina Abdelsalam Mahmoud , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Shereen Abdelmonem Mohamed , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
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| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Soheir |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
