A comparative Study of the possible cardioprotective effects of Erythropoietin in diabetic and uremic cardiomyopathy in rats / (Record no. 57151)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03154cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031528.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160712s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.30.M.Sc.2016.He.C |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Heba Ahmed Hashem Muhammad |
| 245 12 - TITLE STATEMENT | |
| Title | A comparative Study of the possible cardioprotective effects of Erythropoietin in diabetic and uremic cardiomyopathy in rats / |
| Statement of responsibility, etc. | Heba Ahmed Hashem Muhammad ; Supervised Hania Ibrahim Ammar , Muhammad Ali Eashra , Ayman Saieed Soliman |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة مقارنة للتأثير المحتمل للإرثروبويتين في حماية القلب عند مريض اعتلال عضلة القلب الناتج عن السكر و الفشل الكلوي عند الفئران |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Heba Ahmed Hashem Muhammad , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 227 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Physiology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Cardiomyopathy is a common chronic complication associated with diabetes and chronic kidney disease. Erythropoietin (EPO) was reported as a broad spectrum cardioprotective agent. We aim to compare between the effect of long term administration of EPO in prevention or delaying development of diabetic or uremic cardiomyopathy. Diabetes was induced by intraperitoneal (IP) injection of 65mg/kg STZ. Uremia was induced by 5/6 subtotal nephrectomy. EPO treated diabetic and uremic groups were injected with 1000 IU/kg of EPO (IP) twice weekly till the end of the study. At the 12th and the 16th for diabetic and uremic groups respectively heart tissues were collected for pathological examination. Result: compared to sham and EPO treated nephrectomy group the untreated nephrectomy group showed significant decrease in EF% & FS% by the 12th week with more decrease by the 16th week of the study, while EPO treated nephrectomy group show significant decrease in EF% & FS% only by the 16th week compared to sham group but still significantly higher than values of untreated nephrectomy group at the same time interval. Both EPO treated and untreated diabetic groups showed significant decrease in EF% & FS% by the 4th week with further more decrease up to the 12th week of the study. Pathological examination for hearts from EPO treated nephrectomy show significant increase in capillary numbering and decrease in area % of fibrosis compared to untreated nephrectomy and sham group.Conclusion: the beneficial role of EPO as a cardioprotective is differentially activated or inactivated according to the underlying cause of cardiomyopathy |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Diabetic cardiomyopathy |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Erythropoietin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Uremic cardiomyopathy |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ayman Saieed Soliman , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hania Ibrahim Ammar , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Muhammad Ali Eashra , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Enas |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.30.M.Sc.2016.He.C | 01010110069462000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.30.M.Sc.2016.He.C | 01020110069462000 | 22.09.2023 | CD - Rom | 69462.CD |