Evaluation of bone Health among epileptic patients using biochemical markers and DEXA Scan / (Record no. 57198)
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000 -LEADER | |
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fixed length control field | 03288cam a2200349 a 4500 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | EG-GiCUC |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20250223031530.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 160719s2016 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | EG-GiCUC |
Language of cataloging | eng |
Transcribing agency | EG-GiCUC |
041 0# - LANGUAGE CODE | |
Language code of text/sound track or separate title | eng |
049 ## - LOCAL HOLDINGS (OCLC) | |
Holding library | Deposite |
097 ## - Thesis Degree | |
Thesis Level | M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
Classification number | Cai01.11.21.M.Sc.2016.Do.E |
100 0# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Doaa Atef Mostafa Mekkawy |
245 10 - TITLE STATEMENT | |
Title | Evaluation of bone Health among epileptic patients using biochemical markers and DEXA Scan / |
Statement of responsibility, etc. | Doaa Atef Mostafa Mekkawy ; Supervised Ebtesam Mohamed Fahmy , Rania Shehata Mohamed , Laila Ahmed Rashed |
246 15 - VARYING FORM OF TITLE | |
Title proper/short title | تقييم صحة العظام في مرضى الصرع باستخدام دلالات بيوكيميائية و اشعة دكسا |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Cairo : |
Name of publisher, distributor, etc. | Doaa Atef Mostafa Mekkawy , |
Date of publication, distribution, etc. | 2016 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 167 P. : |
Other physical details | charts , facsimiles ; |
Dimensions | 25cm |
502 ## - DISSERTATION NOTE | |
Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Neuropsychiatry |
520 ## - SUMMARY, ETC. | |
Summary, etc. | The study was carried on thirty epileptic patients and thirty matched normal control subjects. Measurement of serum: calcium, phosphorus, vitamin D, parathormone and alkaline phosphatase levels were done for included subjects. DEXA scan was performed also at three regions (lumbar spine, left femur and left radius) for all subjects.Results: There was a statistically highly significant difference between epileptic patients and control subjects regarding all laboratory markers of bone health. Serum calcium, phosphorus, and vitamin D were significantly lower, whereas, serum parathormone (PTH) and alkaline phosphatase (ALP) were significantly higher in epileptic patients compared to normal subjects. Bone mineral density abnormalities were detected in 22 patients (73.4%) (Seventeen patients (56.7%) had osteopenia and five patients (16.7%) had osteoporosis). A statistically significant difference as regards DEXA scan measurements at different regions was detected between epileptic patients and normal control subjects. It was found that epileptic patients receiving enzyme inducers had significantly lower serum (calcium, phosphorous and vit. D) And bone mineral density results in comparison to those on enzyme inhibitor AEDs. There was a significant positive correlation between (bone mineral density and T- score) results and serum level of calcium, phosphorous and vit. D, while a significant negative correlation was detected between (BMD and T-score) results and serum alkaline phosphatase and duration of therapy. While there was no correlation between (BMD and T-score) results and age, age at disease onset nor parity. An annual increased risk of 1.366 was found in epileptic patients receiving AEDs in comparison to normal controls.Conclusion: Abnormal bone health is more common in epileptic patients compared to normal subjects. These abnormalities may be attributed mainly to prolonged intake of AEDs especially enzyme inducers |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
Additional physical form available note | Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | AEDs |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | DEXA |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Epilepsy |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Ebtesam Mohamed Fahmy , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Laila Ahmed Rashed , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Rania Shehata Mohamed , |
Relator term | |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Enas |
Reviser | Cataloger |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Nazla |
Reviser | Revisor |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Dewey Decimal Classification |
Koha item type | Thesis |
Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
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Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.21.M.Sc.2016.Do.E | 01010110069473000 | 22.09.2023 | Thesis | ||
Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.21.M.Sc.2016.Do.E | 01020110069473000 | 22.09.2023 | CD - Rom | 69473.CD |