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Evaluation of bone Health among epileptic patients using biochemical markers and DEXA Scan / (Record no. 57198)

MARC details
000 -LEADER
fixed length control field 03288cam a2200349 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250223031530.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 160719s2016 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.11.21.M.Sc.2016.Do.E
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Doaa Atef Mostafa Mekkawy
245 10 - TITLE STATEMENT
Title Evaluation of bone Health among epileptic patients using biochemical markers and DEXA Scan /
Statement of responsibility, etc. Doaa Atef Mostafa Mekkawy ; Supervised Ebtesam Mohamed Fahmy , Rania Shehata Mohamed , Laila Ahmed Rashed
246 15 - VARYING FORM OF TITLE
Title proper/short title تقييم صحة العظام في مرضى الصرع باستخدام دلالات بيوكيميائية و اشعة دكسا
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Doaa Atef Mostafa Mekkawy ,
Date of publication, distribution, etc. 2016
300 ## - PHYSICAL DESCRIPTION
Extent 167 P. :
Other physical details charts , facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Neuropsychiatry
520 ## - SUMMARY, ETC.
Summary, etc. The study was carried on thirty epileptic patients and thirty matched normal control subjects. Measurement of serum: calcium, phosphorus, vitamin D, parathormone and alkaline phosphatase levels were done for included subjects. DEXA scan was performed also at three regions (lumbar spine, left femur and left radius) for all subjects.Results: There was a statistically highly significant difference between epileptic patients and control subjects regarding all laboratory markers of bone health. Serum calcium, phosphorus, and vitamin D were significantly lower, whereas, serum parathormone (PTH) and alkaline phosphatase (ALP) were significantly higher in epileptic patients compared to normal subjects. Bone mineral density abnormalities were detected in 22 patients (73.4%) (Seventeen patients (56.7%) had osteopenia and five patients (16.7%) had osteoporosis). A statistically significant difference as regards DEXA scan measurements at different regions was detected between epileptic patients and normal control subjects. It was found that epileptic patients receiving enzyme inducers had significantly lower serum (calcium, phosphorous and vit. D) And bone mineral density results in comparison to those on enzyme inhibitor AEDs. There was a significant positive correlation between (bone mineral density and T- score) results and serum level of calcium, phosphorous and vit. D, while a significant negative correlation was detected between (BMD and T-score) results and serum alkaline phosphatase and duration of therapy. While there was no correlation between (BMD and T-score) results and age, age at disease onset nor parity. An annual increased risk of 1.366 was found in epileptic patients receiving AEDs in comparison to normal controls.Conclusion: Abnormal bone health is more common in epileptic patients compared to normal subjects. These abnormalities may be attributed mainly to prolonged intake of AEDs especially enzyme inducers
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term AEDs
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term DEXA
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Epilepsy
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Ebtesam Mohamed Fahmy ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Laila Ahmed Rashed ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Rania Shehata Mohamed ,
Relator term
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a>
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Enas
Reviser Cataloger
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.11.21.M.Sc.2016.Do.E 01010110069473000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.11.21.M.Sc.2016.Do.E 01020110069473000 22.09.2023 CD - Rom 69473.CD