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A Micro-anatomical study of the effect of rifampicin on the liver of adult albino rat and the possible protective role of vitamin "E"b / (Record no. 57585)

MARC details
000 -LEADER
fixed length control field 02611cam a2200325 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 160829s2016 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.11.02.M.Sc.2016.Re.M
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Reda Ibrahim Abdelmoheimen
245 12 - TITLE STATEMENT
Title A Micro-anatomical study of the effect of rifampicin on the liver of adult albino rat and the possible protective role of vitamin "E"b /
Statement of responsibility, etc. Reda Ibrahim A. Elmoheimen ; Supervised Wafik Halim Nessim , Maha Hussein Ashmawy , Mohamed Ehab Eldin Moustafa
246 15 - VARYING FORM OF TITLE
Title proper/short title دراسة تشريحية دقيقة عن تأثيرعقار الريفامبيسين على كبد الفأر الأبيض البالغ والدور الوقائى المحتمل لفيتامين"هـ
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Reda Ibrahim A. Elmoheimen ,
Date of publication, distribution, etc. 2016
300 ## - PHYSICAL DESCRIPTION
Extent 95 P. :
Other physical details charts , facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Anatomy
520 ## - SUMMARY, ETC.
Summary, etc. Rifampicin is one of the main drugs used for treatment of tuberculosis. However Rifampicin was proved to have adverse side effects such as hepatotoxicity. The present study was carried out to detect the histopathological effects of RMP on the liver of adult albino rats and to study the possible protective role of vitamin "E" in prevention of RMP-induced hepatotoxicity. Rifampicin (RMP) treated group showed various degrees of histopathological changes in the form of dilatation and congestion of the hepatic sinusoids, numerous Von Kupffer cells and inflammatory cellular infiltration. The hepatocytes showed intracytoplasmic vacuolations, nuclear pyknosis, necrosis and apoptosis. The liver showed obvious increase in fibrous tissue amount. Glycogen depletion and marked increase in acid phosphatase enzyme activity were noticed in the liver cells. The hepatotoxicity of Rifampicin increased by prolongation of its administration.With the use of vitamin E in conjunction with RMP the liver of the rats of group IV showed remarkable improvement of the histological and histochemical pattern.
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Liver
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Rat
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Rifampicin
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Maha Hussein Ashmawy ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mohamed Ehab Eldin Moustafa ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Wafik Halim Nessim ,
Relator term
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Soheir
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.11.02.M.Sc.2016.Re.M 01010110069619000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.11.02.M.Sc.2016.Re.M 01020110069619000 22.09.2023 CD - Rom 69619.CD