Theoretical, experimental and biological activity studies of some triazolopyrimidine derivatives / (Record no. 57709)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02964cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031545.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160908s2015 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.11.M.Sc.2015.Kh.T |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Khaled Saad Abdullah Abdelrahman |
| 245 10 - TITLE STATEMENT | |
| Title | Theoretical, experimental and biological activity studies of some triazolopyrimidine derivatives / |
| Statement of responsibility, etc. | Khaled Saad Abdullah Abdelrahman ; Supervised Hussein M. A. Moustafa , Mohamed E. Elshakre , Huwaida M. E. Hassaneen |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسات نظرية و عملية لبعض مشتقات التريازولوبيريميدين و نشاطها البيولوجي |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Khaled Saad Abdullah Abdelrahman , |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 127 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Physical Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | 5,7-diphenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine and six of its derivatives are investigated experimentally and theoretically in Gas phase, Dioxane and DMF. The parent compound is investigated in details with its subsystems to predict the most active moiety responsible for the ground state properties of the parent compound and to study the different conjugation extends in the parent compound. The calculations of compounds 1-7 show that all the compounds are non-planar. The ground state properties of compounds 1-7 optimized at B3LYP/6-311G(df,pd) show that compound 2, which contains the nitro group, is the highest reactive compound, while compound 7 is the most polar one. The observed UV spectra in Dioxane and DMF of compounds 1-7 show that the difference in the spectral features of the studied compounds can be attributed to the extent of the hyper conjugation of the triazolo[1,5- a]pyrimidine moiety and the nature of the substituent of the two phenyl groups. Band maxima (n ) and intensities of the spectra are max found to have solvent dependence reflected as blue and red shifts. The theoretical spectra computed at TD-B3LYP/6-311G(d,p) in gas phase, Dioxane and DMF predict the electronic transition characters for the experimental bands observed. Biological activity calculated show no antifungal activity and a very weak antibacterial activity, where no noticeable relation can be found between the physical properties of the studied compounds and their biological activity. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | DFT/B3LYP |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | TD-DFT |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Triazolo[1,5-a]pyrimidine |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hussein Mohamed Ahmed Moustafa , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Huwaida Mohamed Elsayed Hassaneen , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Elsayed Elshakre , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Soheir |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.11.M.Sc.2015.Kh.T | 01010110069673000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.11.M.Sc.2015.Kh.T | 01020110069673000 | 22.09.2023 | CD - Rom | 69673.CD |