Pharmacognostical study of rumex nervosus vahl. family (polygonaceae) growing in Yemen / (Record no. 58015)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03837cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 161011s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.07.M.Sc.2016.Sa.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sami Mohammed Yahya Alsunafi |
| 245 10 - TITLE STATEMENT | |
| Title | Pharmacognostical study of rumex nervosus vahl. family (polygonaceae) growing in Yemen / |
| Statement of responsibility, etc. | Sami Mohammed Yahya Alsunafi ; Supervised Mohammed Saied Hifnawy , Kadriya Shafik Eldeeb , Hanaa Hassan Eid |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة عقاقيرية لنبات العثرب العائلة (البطباطية) الذي ينمو في اليمن |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Sami Mohammed Yahya Alsunafi , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 185 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Rumex nervosus Vahl. is a perennial herb distributed in Yemen, Saudi Arabia, Ethiopia, Somalia, Kenya and Tanzania. This study includes botanical study on the root, stem and leaf of Rumex nervosus Vahl., biological and phytochemical studies on the aerial parts of the plant. The ethanolic extract (70%) showed potent cytotoxic activity against colon and skin carcinoma cell lines, moderate activity against breast and intestinal carcinoma cell lines and In the normal fibroblast cells were affected to a much lesser extent. Petroleum ether, dichloromethane and ethyl acetate fractions of the aerial parts showed moderate anti-bacterial activity against both Gram +ve and Gram {u2013}ve bacteria when compared to ampicillin as standard. The ethanolic extract (70%) and its fractions (ethyl acetate and n-butanol) significantly inhibited the activity of DPPH radicals in a dose-dependent manner, the most potent was the ethyl acetate fraction followed by the ethanolic extract (70%). The ethanolic extract (70%) and its fractions (petroleum ether, dichloromethane, ethyl acetate and n-butanol) showed significant anti-inflammatory activity at a dose of 100 mg/kg b.wt. compared to indomethacin (20 mg/kg b.wt.), after 4 hr. the ethyl acetate fraction showed the highest anti-inflammatory activity followed by the ethanolic extract (70%). The ethanolic extract (70%) and its fractions (petroleum ether, dichloromethane, ethyl acetate and n-butanol) exhibited significant antioxidant activity (in-vivo) as the level of blood glutathione in diabetic rats was restored after the oral administration (100mg/kg b.wt.) of them. The ethyl acetate fraction showed the highest antioxidant activity followed by the ethanolic extract (70%) compared to vitamin E (7.5mg/kg b.wt.). Phytochemical investigation of the ethyl acetate fraction lead to isolation and identification of five phenolic compounds (kaempferol, quercetin, gallic acid, hyperoside and quercetin 3-O-(6{uF0A2}{uF0A2}-acetyl)-galactoside) isolated for the first time from Rumex nervosus Vahl. Total flavonoidal content of the aerial parts was 19.63 mg QE/g dry powder whereas, total phenolic content was 39.28mg GAE/g dry powder. HPLC analysis of phenolic compounds in the aerial parts of the plant lead to the identification and quantification of twenty four phenolic compounds: ten flavonoids among which hesperidin and quercetin were the major compounds and twelve phenolic acids among which gallic acid was the major followed by p-hydoxy benzoic acid |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Pharmacognostical study |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Rumex nervosus vahl. family (polygonaceae) growing |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Yemen |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hanaa Hassan Eid , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kadriya Shafik Eldeeb , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohammed Saied Hifnawy , |
| Relator term | |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Enas |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.07.M.Sc.2016.Sa.P | 01010110069787000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.07.M.Sc.2016.Sa.P | 01020110069787000 | 22.09.2023 | CD - Rom | 69787.CD |