Applications of laser technologies in nano genotoxicity of gold particles in mammals : (Record no. 58354)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03127cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031606.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 161029s2015 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.24.10.M.Sc.2015.Mo.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mostafa Fathy Abdelelnaeim Zedan |
| 245 10 - TITLE STATEMENT | |
| Title | Applications of laser technologies in nano genotoxicity of gold particles in mammals : |
| Remainder of title | In Vitro study / |
| Statement of responsibility, etc. | Mostafa Fathy Abdelelnaeim Zedan ; Supervised Mona Abdelaziz , Mohamed Amr H. Elnoury , Samia A. Shouman |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تطبيقات تكنولوجيا الليزر فى السمية الوراثية النانوية لجسيمات الذهب فى الثدييات : |
| Remainder of title | دراسة معملية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mostafa Fathy Abdelelnaeim Zedan , |
| Date of publication, distribution, etc. | 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 104 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - National Institute of Laser Enhanced Sciences - Department of Laser Applications |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | In the last decades, nanotechnology has become a key word in scientific research as well as in the public interest and it is considered as the critical research technology of the 21st century. Gold nanoparticles have been proven to be powerful tools in various nanomedicinal applications. Consequently, the study of cytotoxicity and genotoxicity of gold nanoparticles has been emerged as an important issue. In this study, we have studied the cytotoxicity (using MTT assay) and genotoxicity (using comet assay) of gold nanospheres and nanorods in human hepatocellular carcinoma cell line (HepG2). The experimental conditions such as nanoparticles preparation (surface modification), laser power, time of exposure, and concentration of the gold nanoparticles have been studied . Non-PEGylated and PEGylated Au nanospheres with Poly (ethylene glycol) methyl ether thiol (m-PEG-SH), were synthesized by citrate reduction method. Also, Au nanorods were prepared using the seed-mediated method and modified with m-PEG-SH. The prepared nanoparticles were characterized using UV-Vis. spectroscopy, dynamic light scattering (DLS) and transmission electron microscopy (TEM). The synthesized Au nanoparticles before and after the PEGylation showed very good stability for both after different types of low intensity laser exposure and in the cell culture supplementary media (RPMI). The potential cytotoxicity of the synthesized Au nanoparticles before and after PEGylation in dark conditions showed that there is no significant difference in cell viability between non-PEGylated and PEGylated Au nanospheres at the same concentration |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Gold particles |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Laser technologies |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Nano genotoxicity |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Amr Hussain Elnoury , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mona Abdelaziz , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Samia Abdelsamea Shouman , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Soheir |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.24.10.M.Sc.2015.Mo.A | 01010110069882000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.24.10.M.Sc.2015.Mo.A | 01020110069882000 | 22.09.2023 | CD - Rom | 69882.CD |