MARC details
000 -LEADER |
fixed length control field |
02536cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
161101s2016 ua d f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
Ph.D |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.10.04.Ph.D.2016.Sa.S |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Samar Kamel Mohamed Khalil |
245 10 - TITLE STATEMENT |
Title |
Some biochemical studies on immune response of chronic kidney disease patients / |
Statement of responsibility, etc. |
Samar Kamel Mohamed Khalil ; Supervised Hassan Abdelhalim H. Amer , Adel M. Elbehairy , Mohamad Ali Warda |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
بعض الدراسات البيوكيميائية على الاستجابة المناعية لمرضى الكلى المزمن |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Samar Kamel Mohamed Khalil , |
Date of publication, distribution, etc. |
2016 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
172 P. : |
Other physical details |
charts ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Biochemistry and Chemistry of Nutrition |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Inflammation and oxidative stress are two faces of one coin in end stage renal disease patients (ESRD) on maintenance hemodialysis. Their interconnection induces anemia complicated with erythropoietin hyporesponsiveness. The biochemical basis behind the resistance to erythropoietin therapy with frequent hemoglobinemia, oxidative stress and iron status have not been fully recovered. Two equal groups (40 patients each) of responders and non-responders to recombinant human erythropoietin therapy (higher than 300 IU / kg / wk of epoetin) were used in the study. Hematological and biochemical analysis of collecting blood and serum samples were performed along with serum electrophoretic protein foot printing. The leukocytes DNA fragmentation was used to evaluate the degree of oxidative insult. Erythropoietin (EPO) good responders showed lower erythrocyte malondialdehyde (E-MDA) level; less pronounced DNA fragmentation of circulating leukocytes than poor responder with elevated hemoglobin, albumin, A / G ratio, total iron, and ferritin levels. Contrariwise, lower erythrocyte superoxide dismutase (E-SOD) and catalase activities in EPO poor responder group than good responder one |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Erythropoietin resistance |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Inflammatory markers |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Oxidative stress |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Adel Mohamed AbuElfetouh Elbehairy , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Hassan Abdelhalim Hassan Amer , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Mohamad Ali Ahmed Warda , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Samia |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |