Formulation and evaluation of biodegradable micro particles containing certain antibiotic / (Record no. 58452)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02565cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031608.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 161105s2016 ua o f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.10.M.Sc.2016.Su.F |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Suzan Amin Abdelrazek Ahmed |
| 245 10 - TITLE STATEMENT | |
| Title | Formulation and evaluation of biodegradable micro particles containing certain antibiotic / |
| Statement of responsibility, etc. | Suzan Amin Abdelrazek Ahmed ; Supervised Mohamed Aly Kassem , Amir Ibrahim Mohamed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | صياغة و تقييم حبيبات دقيقة ذاتية التحلل تحتوى مضاد حيوى معين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Suzan Amin Abdelrazek Ahmed , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 131 P. : |
| Other physical details | photographs ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Industrial Pharmacy |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Clindamycin microspheres were prepared using natural biodegradable polymers sodium alginate, chitosan, eudargit RS100,ethyl cellulose and glycerol mono oleate as matrix for the drug adopting cubic gel dispersion and water in oil emulsion method. From differential scanning calorimetry results, it was found that there are no interactions between clindamycin and the five polymers at solid state while characteristic peaks of drug are disappeared in drug polymer blend films due to transformation of molecular state of drug from crystalline to amorphous form. From X- ray diffraction results, it was found that there are no interactions between clindamycin and five polymers at solid state and drug crystallinity is present, while in all polymers clindamycin film peaks of drug are disappeared and this confirmed DSC result. FTIR spectra did not reveal significant changes (minor shifts) in the characteristic bands of the drug and polymers which indicate the chemical stability of drug during mixing with the five used polymers and the absence of drug polymer interactions. From agar dilution susceptibility test, minimum inhibitory concentration of clindamycin is not changed in presence of polymers, this indicates that polymers have no effect on antimicrobial activity of clindamycin |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Clindamycin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Glycerol mono oleate |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Infrared spectroscopy |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amir Ibrahim Mohamed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Aly Kassem , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.10.M.Sc.2016.Su.F | 01010110070174000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.10.M.Sc.2016.Su.F | 01020110070174000 | 22.09.2023 | CD - Rom | 70174.CD |