MARC details
| 000 -LEADER |
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| fixed length control field |
03063cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
161114s2016 ua h f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
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| Holding library |
Deposite |
| 097 ## - Thesis Degree |
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| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.11.07.M.Sc.2016.Am.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Amr Yusuf Abdellatif |
| 245 10 - TITLE STATEMENT |
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| Title |
Association between single nucleotide polymorphism (C677T) in MTHFR gene and insulin resistance in polycystic ovary syndrome / |
| Statement of responsibility, etc. |
Amr Yusuf Abdellatif ; Supervised Mohamed Shehata Mohamed Abdallah , Heba Nabil Baz , Wael Faek Gamaleldeen |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
التحورات الجينية المتعددة فى الموقع (سى 776 تى) فى جين (إم تى إتش إف أر) وعلاقتها بمقاومة الانسولين فى مرضى تكيس المبايض |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Amr Yusuf Abdellatif , |
| Date of publication, distribution, etc. |
2016 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
78 P. : |
| Other physical details |
facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
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| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Background: Polycystic ovary syndrome is the most common endocrinopathy affecting females of reproductive age, Features include hyperandrogenism, chronic anovulation and polycystic ovaries on ultrasound. insulin resistance is one of the major consequences affecting women with pcos. Aim of the study: The aim of the present work is to study Association between single nucleotide polymorphism (C677T) in MTHFR gene and Polycystic ovary syndrome in patients with or without insulin resistance in comparison to normal healthy controls. Subjects and methods: the study was conducted on eighty patients recruited from outpatient clinic of obstetrics and gynecology department in Kasr Alainy hospital. In addition to 50 sex and age comparable subjects who were taken as a control group.clinical examination, ultrasound and laboratory analysis including total testosterone,fasting and post prandial glucose and insulin and C677T polymorphism in MTHFR gene was detected using polymerase chain reaction restriction fragment length polymorphism PCR-RFLP. Results: Regarding the prevalence of MTHFR C677T genotype among our cases and the corresponding controls, the frequency of the CC, CT and TT was 57.5%, 41.2% and 1.2% respectively in cases, and 70%, 30.0% in the controls respectively. There is no association between single nucleotide polymorphism (C677T) in MTHFR gene and Polycystic ovary syndrome. Regarding the association between C677T and insulin resistance there is significant difference between mutant variant of C677T of MTHFR gene and other alleles in insulin resistant subjects regardless of PCOS patients |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
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| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
C677T - - |
| 653 #4 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
MTHFR gene |
| 653 #4 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Polycystic ovary syndrome |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Heba Nabil Baz , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohamed Shehata Mohamed Abdallah , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Wael Faek Gamal Eldeen , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Soheir |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
