Comparative study of the analgesic, anti- pyretic and anti- inflammatory activities of extra virgin olive oil and ibuprofen and Their combination in different animal models in albino mice / (Record no. 58661)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03553cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031615.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 161117s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.29.Ph.D.2016.Wa.C |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Wallaa Abdelfattah Osman |
| 245 10 - TITLE STATEMENT | |
| Title | Comparative study of the analgesic, anti- pyretic and anti- inflammatory activities of extra virgin olive oil and ibuprofen and Their combination in different animal models in albino mice / |
| Statement of responsibility, etc. | Wallaa Abdelfattah Osman ; Supervised Elsayed Mahmoud Elrokh , Mona Osman Abdelhalim , Dina Ahmed Aly Labib |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة مقارنة لتقييم فعالية زيت الزيتون البكر الممتاز كمسكن للالم و خافض للحرارة و مضاد للالتهاب مقارنة بالايبوبروفين منفصلين و معا على نماذج تجريبية مختلفة مستحدثه في الفئران البيضاء |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Wallaa Abdelfattah Osman , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 149 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pharmacology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Inflammation is a complex series of physiological events designed to repair the damaged tissue caused by injury or infection. It is involved in the development of many diseases. Cardinal signs of inflammation as pain and fever are commonly treated with NSAIDs which have many adverse effects. Recently, there is a new trend towards the natural dietary anti-inflammatory agents which have potential therapeutic effects with less adverse events. Extra virgin olive oil (EVOO) has been documented nowadays to have diverse beneficial effects on human beings. Oleocanthal is a phenolic compound in olive oil which was proved to have similarity with ibuprofen (IBU). Aim of the work: This work was designed to compare the analgesic, antipyretic and anti- inflammatory effects of EVOO with IBU and their combinations on different animal models in mice. Result: The results revealed that the group treated with the combination of EVOO with the therapeutic dose of IBU 100mg/kg showed the highest percentage of inhibition in acetic acid- induced writhing test and in carrageenan-induced paw edema and the lowest rectal temperature in the brewer's yeast induced pyrexia, followed by that using the standard treatment IBU (100mg/kg) separately. Meanwhile, using EVOO alone or in combination with the low dose of IBU (40mg/kg) showed significant results from the disease model (positive control) but their effects were less than the group treated with the standard drug (IBU 100mg/kg). In the carrageenan induced peritonitis, the results revealed that using the combination of EVOO either with the therapeutic dose of IBU (100mg/kg) or with its low dose (40mg/kg) showed the best results in a dose dependent manner, while using olive oil alone decreased significantly most of the measured parameters and its effects was insignificant from the standard treatment IBU (100mg/kg) |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Anti-inflammatory |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Anti-pyretic |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | EVOO |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dina Ahmed Aly Labib , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Elsayed Mahmoud Elrokh , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mona Osman Abdelhalim , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Soheir |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.29.Ph.D.2016.Wa.C | 01010110070354000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.29.Ph.D.2016.Wa.C | 01020110070354000 | 22.09.2023 | CD - Rom | 70354.CD |