The differential role of irisin : (Record no. 58754)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03065cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031617.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 161122s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.30.M.Sc.2016.Sh.D |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Shimaa Magdy Shaban Eid |
| 245 14 - TITLE STATEMENT | |
| Title | The differential role of irisin : |
| Remainder of title | A novel myokine; on insulin sensitivity and learning capacity in exercised induced diabetic rats / |
| Statement of responsibility, etc. | Shimaa Magdy Shaban Eid ; Supervised Maha Mohamed Gamal , Ola Mostafa Tork , Mohamed Ali Eshra |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | الدورالمميز للأيريسين : |
| Remainder of title | المنشط العضلى الحديث: فى الوظائف الادراكية و الإستجابة للانسولين فى الجرذان المصابة بداء السكرى و الممارسة للتمارين الرياضية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Shimaa Magdy Shaban Eid , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 147 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Physiology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Type 2 diabetes mellitus is a global health problem which still needs to be solved. Irisin, an exercise induced myokine, may have broad implications on metabolism and energy homeostasis. The aim of this work was to investigate irisin expression and its receptor and the signaling pathway in relation to cognitive functions to allow a better understanding of its role in exercised diabetic model. Forty adult male albino rats were divided equally into four groups as follows: (1) control group, (2) diabetic sedentary group, (3) chronic exercised diabetic group, (4) acute exercised diabetic group. Cognitive functions were assessed in all groups in T- maze. After scarification, gastrocnemius muscles, whole brains, and abdominal adipose tissues were excised for measurement of gene expression of; muscle irisin, brain irisin receptors, brain derived neurotrophic factor (BDNF) and adipose tissue uncoupling protein 1 (UCP1). In addition MAPK acitivity in brain and adipose tissue were measured. Muscle irisin expression was significantly elevated in chronic and acute exercised diabetic rats compared to diabetic sedentary rats. Significant positive correlations existed between muscle irisin mRNA expression patterns versus brain irisin receptor expression, BDNF, brain MAPK activity as well as cognitive performance together with improvement in insulin sensitivity and lipid profile. On the other hand, although, muscle irisin was correlated positively with adipose MAPK activity, it was negatively correlated with adipose UCPI |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Brain derived neurotrophic factor |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Exercise |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Irisin |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maha Mohamed Gamal , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Ali Eshra , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ola Mostafa Tork , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.30.M.Sc.2016.Sh.D | 01010110070303000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.30.M.Sc.2016.Sh.D | 01020110070303000 | 22.09.2023 | CD - Rom | 70303.CD |