Design and evaluation of econazole nitrate nanoparticles / (Record no. 58805)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02346cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031619.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 161127s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.08.M.Sc.2016.Am.D |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Amr Maged Ibrahim |
| 245 10 - TITLE STATEMENT | |
| Title | Design and evaluation of econazole nitrate nanoparticles / |
| Statement of responsibility, etc. | Amr Maged Ibrahim ; Supervised Mahmoud M. Ghrab , Azza Ahmed Mahmoud |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تصميم و تقييم جزيئات نانومترية لعقار نترات الإكونازول |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Amr Maged Ibrahim , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 236 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc..) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Econazole nitrate is considered the first generation of azole antifungal agents revolutionized the treatment of mucosal and invasive fungal infections. Furthermore, azoles are still the most widely used group of antifungal agents which is classified as imidazole or triazoles antifungal drug that is used for the treatment of topical fungal infections caused by Candida albicans and tinea. Econazole nitrate is a water insoluble drug that create complicated barrier for formulating it in an ocular drug delivery system. Consequently, the rationale of this study was to develop econazole nitrate nanoparticles by nano-spray drying process to increase dissolution of the drug. The effect of using methyl-Ý-cyclodextrin and hydroxylpropyl-Ý-cyclodextrin as carriers for econazole nitrate nanoparticles prepared by nano-spray dryer was explored in this work. Stabilizers were also used as polyethylene oxide, polyvinylpyrrolidone k30, poloxamer 407, Tween 80 and Cremophor EL. Further modifications were done in order to increase the nanoparticles retention time in the eye and to increase drug bioavailability in the tears of Albino rabbits |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Econazole nitrate |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Nanoparticles |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Pharmaceutics |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Azza Ahmed Mahmoud , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mahmoud Mohamed Ghrab , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Soheir |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.08.M.Sc.2016.Am.D | 01010110070387000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.08.M.Sc.2016.Am.D | 01020110070387000 | 22.09.2023 | CD - Rom | 70387.CD |