Characterization of new sensors for itopride hydrochloride and mosapride citrate in their pharmaceutical preparations / (Record no. 59532)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02725cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031642.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170122s2016 ua h f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.08.M.Sc.2016.Ad.C |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Adel Madbouly Hassnain Mohamed |
| 245 10 - TITLE STATEMENT | |
| Title | Characterization of new sensors for itopride hydrochloride and mosapride citrate in their pharmaceutical preparations / |
| Statement of responsibility, etc. | Adel Madbouly Hassnain Mohamed ; Supervised Nour Eldin Tawfik Abdelghani , Rasha Mohamed Elnashar |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة خصائص محسات جديدة لا يتوبرايد هيدروكلوريد و موزابرايد فى مستحضرتهما الصيدلانية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Adel Madbouly Hassnain Mohamed , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 160 P. : |
| Other physical details | facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Analytical Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The present work describes the use of sensors based on molecularly imprinted polymer (MIP) for the electrochemical determination of Itopride hydrochloride (Itoh) and mosapride citrate (MC). To optimize the synthesis of MIPs, first, computational studies were conducted to determine the most suitable functional monomer to be used and the optimum ratio of template to functional monomer in the synthesis, then MIPs with different ratios were synthesized by bulk polymerization following the non-covalent approach. The rebinding of the templates to the synthesized MIPs was evaluated by equilibrium batch rebinding assays. Finally, the MIP with the highest binding capacity was chosen to be incorporated as an additive in sensors for the electrochemical determination of the two drugs. The MIP chosen was the one prepared with the ratio of (template: functional monomer: crosslinker) 1:8:40 for Itoh and MC. For both drugs, methacrylic acid was used as functional monomer and ethylene glycol dimethacrylate or divinyl benzene were used as crosslinkers for Itoh and MC, respectively. The modified sensors were successfully used in the quantification of the drugs in pure solution, pharmaceutical preparations and spiked biological samples (urine and plasma) using the standard additions method with high accuracy and precision |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Itopride hydrochloride |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Molecularly imprinted polymer |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Mosapride citrate |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nour Eldin Tawfik Abdelghani , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rasha Mohamed Elnashar , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.08.M.Sc.2016.Ad.C | 01010110070767000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.08.M.Sc.2016.Ad.C | 01020110070767000 | 22.09.2023 | CD - Rom | 70767.CD |