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Analysis of genetic association of angiotensin-converting enzyme gene with multiple sclerosis / (Record no. 59536)

MARC details
000 -LEADER
fixed length control field 02442cam a2200325 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 170122s2016 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.11.03.M.Sc.2016.Ma.A
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Marwa Mohamed Abdelhamid
245 10 - TITLE STATEMENT
Title Analysis of genetic association of angiotensin-converting enzyme gene with multiple sclerosis /
Statement of responsibility, etc. Marwa Mohamad Abdelhamid ; Supervised Salwa Fayez Hasan , Marwa Farghali Ahmed , Rania Elsayed Hussein
246 15 - VARYING FORM OF TITLE
Title proper/short title تحليل الارتباط الجيني بين جين الانزيم المحول للأنجيوتنسين و مرض التصلب المتعدد بالجهاز العصبي
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Marwa Mohamed Abdelhamid ,
Date of publication, distribution, etc. 2016
300 ## - PHYSICAL DESCRIPTION
Extent 98 P. :
Other physical details charts , facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry
520 ## - SUMMARY, ETC.
Summary, etc. Background: Increased activity of angiotensin-converting enzyme (ACE) in the blood and cerebrospinal fluid of patients with multiple sclerosis (MS) suggested that ACE may play a role in the pathogenesis and progression of MS. Objectives: To assess the relation between ACE gene I/D polymorphism and prevalence of MS in Egyptian patients and to investigate its possible association with disease severity and progression. Also to assess the relation between TNF-Ü and MS.Subjects and Methods: This study was conducted on 60 MS patients and 50 healthy controls. Polymerase chain reaction (PCR) was applied to detect ACE gene I/D polymorphism. TNF-Ü levels were measured by ELISA.Results: There was no statistical significant difference in the distribution of ACE I/D genotypes (p = 0.115) or in the allelic frequencies (p = 0.067) between patients with MS and control subjects. Also, there was no statistical significant difference in TNF-Ü levels between MS patients and control (p=0.113). Conclusion: There is no relation between ACE I/D polymorphism and MS susceptibility and/or severity in the study population
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term ACE gene
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Multiple sclerosis
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term TNF-Ü
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Marwa Farghali Ahmed ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Rania Elsayed Hussein ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Salwa Fayez Hasan ,
Relator term
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Enas
Reviser Cataloger
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.11.03.M.Sc.2016.Ma.A 01010110070582000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.11.03.M.Sc.2016.Ma.A 01020110070582000 22.09.2023 CD - Rom 70582.CD