Activated regulatory and effector T cells imbalance in chronic HCV : (Record no. 59730)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02634cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031647.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170207s2016 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.03.Ph.D.2016.Ah.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Reda Sayed |
| 245 10 - TITLE STATEMENT | |
| Title | Activated regulatory and effector T cells imbalance in chronic HCV : |
| Remainder of title | Relation to autoimmunity / |
| Statement of responsibility, etc. | Ahmed Reda Sayed ; Supervised Hanan Hassan Fouad , Eman Medhat Hassan , Ghada Mahmoud Abdelaziz |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | الخلل فى الخلايا التائية التنظيميه المنشطه و المستجيبه فى مرضى فيروس سى الكبدى المزمن : |
| Remainder of title | و العلاقه بالمناعة الذاتية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Ahmed Reda Sayed , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 99 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Hepatitis C virus (HCV) is remarkable at disrupting human immunity to establish chronic infection. Chronic HCV is associated with T cell imbalance, Also IFN-Ü and/or ribavirin used in the treatment of chronic HCV cause teffs / tregs imbalance and this imbalance is associated with autoantibodies production with or without autoimmune hepatitis. The main objectives of the present study to investigate how Tregs are regulated in patients chronically infected with HCV (by measuring Tregs markers granzyme 2, CD69 and FoxP3) and to investigate the effect of IFN-a and/or ribavirin on Teffs/Tregs balance and to study the association of Teffs / Tregs balance with the presence of antinuclear antibody (by measuring Teffs markers TNFRSF4, CD4, CD25 and INFG). The study was conducted on 120 patients classified into 4 groups; Group I. (30 persons): included healthy subjects served as a control group, Group II. (30 patients): included treatment naïve HCV chronically infected patients, Group III. (30 patients): included HCV chronically infected patients treated with IFN- Ü and/or ribavirin (the standard of care therapy), Group VI. (30 patients): included HCV chronically infected patients with associated non organ specific autoantibody |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Autoimmunity |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | HCV |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | T cells |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Eman Medhat Hassan , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ghada Mahmoud Abdelaziz , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hanan Hassan Fouad , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.03.Ph.D.2016.Ah.A | 01010110071038000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.03.Ph.D.2016.Ah.A | 01020110071038000 | 22.09.2023 | CD - Rom | 71038.CD |