Influence of cyp3a5 gene polymorphism on cyclosporine dosage in kidney transplant recipients / (Record no. 59731)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02342cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170207s2016 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.07.M.Sc.2016.Ma.I |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Maha Sami Saad Almansi |
| 245 10 - TITLE STATEMENT | |
| Title | Influence of cyp3a5 gene polymorphism on cyclosporine dosage in kidney transplant recipients / |
| Statement of responsibility, etc. | Maha Sami Saad Almansi ; Supervised Dina Mohamed Elabd , Tarek Fayad , Amaal Abdo Abdelaal |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | فى مرضى زراعة الكلى Cyclosporine على جرعات عقار CYP3A5 تأثير التعدد الشكلى لجين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Maha Sami Saad Almansi , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 122 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Renal transplantation is currently the treatment of choice for end-stage renal disease (ESRD). The complications of the renal transplantation are rejection, nephrotoxicity of calcineurin inhibitors (CNI), and recurrence of native kidney disease. Cyclosporine (CsA) is a member of CNI family, which is widely used as a basic component of immunosuppressive regimens to prevent allograft rejection in solid organ transplantation. CYP3A4, and CYP3A5 are the main genes involved in the pharmacokinetics of CNI. Several single nucleotide polymorphisms were identified in these genes such as CYP3A5 (6986A > G). Aim of the work: To assess the impact of CYP3A5 (6986A > G) SNP on the dose and blood level of CsA among Egyptian renal transplant recipients after three months of transplantation. Subjects and methods: A total of 50 renal transplant recipients receiving CsA subjected to genotyping analysis of CYP3A5 (6986A > G) by Real-time PCR using the TaqMan SNP genotyping assay. The C0 and C2 of CsA were measured and their relationships with CYP3A5 genotypes were assessed |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cyclosporine |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | CYP3A5 polymorphism |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Renal transplantation |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amaal Abdo Abdelaal , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dina Mohamed Elabd , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tarek Fayad , |
| Relator term | |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.07.M.Sc.2016.Ma.I | 01010110071039000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.07.M.Sc.2016.Ma.I | 01020110071039000 | 22.09.2023 | CD - Rom | 71039.CD |