MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02706cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
170208s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.11.28.M.Sc.2016.Mo.R |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohamed Hamdy Mohamed Alkomy |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Role of vitamin D receptor gene polymorphisms (BsmI and FokI) in Egyptian children with Familial Mediterranean fever / |
| Statement of responsibility, etc. |
Mohamed Hamdy Mohamed Alkomy ; Supervised Samia Salah Eldin Mahmoud , Yomna Mohamed Farag , Mona Mohsen Abdulsalam |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
فى الأطفال المصريين المصابين بحمى البحر المتوسط (FokI و BsmI)دور تعدد الشكل الجينى لمستقبلة الفيتامن - د |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Mohamed Hamdy Mohamed Alkomy , |
| Date of publication, distribution, etc. |
2016 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
120 P. : |
| Other physical details |
charts , facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Background: Familial Mediterranean fever (FMF) is an autosomal recessive auto-inflammatory disease. Vitamin D, a vital hormone with immune modulatory function, acts through a nuclear receptor (VDR). Several polymorphisms of VDR gene have been associated with many inflammatory and autoimmune diseases. Objective: The aim of this study was to determine the possible association between VDR gene polymorphisms (BsmI and FokI) and FMF susceptibility in a cohort of Egyptian FMF patients and to correlate these polymorphisms with different clinical and laboratory features of the disease. Methods: 50 patients FMF being followed in Pediatric Rheumatology clinic, Cairo University, were studied. Patients and 40 age matched controls were genotyped for BsmI and FokI polymorphisms by Real time Polymerase Chain Reaction (PCR) technique. Results: There was no significant difference between patients and controls for VDR BsmI and FokI genotypes, alleles, haplotypes (p> 0.05).No association was found of BsmI or FokI genotypes with some performed disease determinants except for a marginal association between CC , CT of BsmI and occurrence of abdominal pain (p = 0.047). Conclusion: Our study showed that BsmI and FokI were not associated with FMF susceptibility but revealed a possible association between BsmI and occurrence of abdominal pain |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
BsmI |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
FMF |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
FokI |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mona Mohsen Abdulsalam , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Samia Salah Eldin Mahmoud , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Yomna Mohamed Farag , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Shaima |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
