MARC details
000 -LEADER |
fixed length control field |
02969cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
170209s2016 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.11.28.M.Sc.2016.Mo.O |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Mohamed Ahmed Mohamed Naeem |
245 10 - TITLE STATEMENT |
Title |
Oxidants and antioxidants status and Viral Hepatitis C infection among patients with Sickle Cell Diseas / |
Statement of responsibility, etc. |
Mohamed Ahmed Mohamed Naeem ; Supervised Mohamed Hesham Safouh , Amina Abdesalam Mahmoud , Hoda Mostafa Yassen Elazizy |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
حالة الأكسدة ومضادات الأكسدة وعدوى التهاب الكبد الفيروسي سي بين المرضى الذين يعانون من مرض فقر الدم المنجلي |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Mohamed Ahmed Mohamed Naeem , |
Date of publication, distribution, etc. |
2016 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
123 P. : |
Other physical details |
charts , facsimiles ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Objectives: The present study was conducted to evaluate the oxidant- antioxidant status of SCD patients and to study the impact of HCV sero- positivity on the oxidant-antioxidant status among SCD patients Methods: The serum levels of total antioxidant(TAO), paraoxonase (PON), catalase(CAT) and malondialdehyde(MDA) were estimated in 50 patients with established diagnosis of SCA in steady state disease (21 males and 29 females) and 30 apparently healthy subjects age & sex matched controls. Results: Mean serum MDA and CAT in SCD cases were significantly higher (P= 0.001; 0.01 respectively) while mean TAO, and PON1 levels were significantly lower among SCD cases compared to controls (p=0.001). No significant differences in mean levels of CAT, PON, TAO and MDA in SCD males when compared with SCD females (P{u02C3} 0.05). But we found that mean MDA in males was significantly lower than females (P=0.03). No significant differences in the mean levels of CAT, PON, TAO and MDA between HCV positive and HCV negative SCD patients (P{u02C3} 0.05). No significant differences in the mean levels of CAT, PON, TAO and MDA in SCD cases on hydroxyurea (HU) and those not receiving HU (P{u02C3} 0.05). No significant correlations were detected between CAT, PON, TAO, MDA and different patient variables (P{u02C3} 0.05).Conclusions: Oxidative stress is evident in SCD patients of both genders. HCV seropositivity or HCV-RNA positivity had no evidence of a more severe oxidative stress. Hydroxyurea did not play a significant role as an antioxidant among our patients |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Antioxidants |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Catalase |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Paraoxonase |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Amina Abdelsalam Mahmoud , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Hoda Mostafa Yassen Elazizy , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Mohamed Hesham Safouh , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Shaima |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |