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Effect of melatonin supplemented at the light or dark period on recovery of sciatic nerve injury in rats / (Record no. 59957)

MARC details
000 -LEADER
fixed length control field 02923cam a2200349 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250223031653.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 170225s2016 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.11.16.M.Sc.2016.En.E
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Enas Ezzat Mohammed Rateb
245 10 - TITLE STATEMENT
Title Effect of melatonin supplemented at the light or dark period on recovery of sciatic nerve injury in rats /
Statement of responsibility, etc. Enas Ezzat Mohammed Rateb ; Supervised Samah Elattar , Nashwa Eltablawy , Shimaa Nasr
246 15 - VARYING FORM OF TITLE
Title proper/short title تأثير إعطاء الميلاتونين فى فترات الضوء و الظلام على التعافى من إصابة العصب الوركى فى الفئران
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Enas Ezzat Mohammed Rateb ,
Date of publication, distribution, etc. 2016
300 ## - PHYSICAL DESCRIPTION
Extent 184 P. :
Other physical details charts , facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Histology
520 ## - SUMMARY, ETC.
Summary, etc. Peripheral nerve injuries are commonly encountered in clinical practice due to several causes such as accidental trauma or surgery. All of these traumas can cause temporary or life-long disabilities that can subsequently lead to social or economic problems. Melatonin, the secretory product of the pineal gland exhibits an array of biological activities, including antioxidant and anti-inflammatory actions. The aim of the present study was to investigate the effect of melatonin on the recovery of sciatic nerve after injury with comparing its effect when it is given to the rats in the light or the dark period. Forty adult male wistar albino rats were randomly allocated into 4 groups, each one contains 10 rats: group 1 (control), group 2 (nerve injury), group 3 (nerve injury+melatonin given at light) and group 4 (nerve injury + melatonin given at dark). Nerve injury was initiated by clamping the sciatic nerves with a standard temporary aneurismal clip for 2 minutes for all groups except the control one. Sciatic functional index (SFI) was measured preoperatively for all groups and nerve injury was confirmed by measuring the sciatic functional index postoperatively. Melatonin was given as 50 mg/kg BW intraperitoneally daily for 6 weeks. Recovery of the function was analyzed by functional analysis [Sciatic function index], electrophysiological analysis [Nerve Conduction Velocity (NCV) and force of muscle contraction] and biochemical analysis by measuring - superoxide dismutase (SOD), Interleukin 1B (IL-1B), Nerve growth factor (NGF), and bcl-2
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Apoptosis
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Melatonin
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Nerve injury
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Nashwa Eltablawy ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Samah Elattar ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Shimaa Nasr ,
Relator term
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a>
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Samia
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.11.16.M.Sc.2016.En.E 01010110071113000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.11.16.M.Sc.2016.En.E 01020110071113000 22.09.2023 CD - Rom 71113.CD