Effect of melatonin supplemented at the light or dark period on recovery of sciatic nerve injury in rats / (Record no. 59957)
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000 -LEADER | |
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fixed length control field | 02923cam a2200349 a 4500 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | EG-GiCUC |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20250223031653.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 170225s2016 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | EG-GiCUC |
Language of cataloging | eng |
Transcribing agency | EG-GiCUC |
041 0# - LANGUAGE CODE | |
Language code of text/sound track or separate title | eng |
049 ## - LOCAL HOLDINGS (OCLC) | |
Holding library | Deposite |
097 ## - Thesis Degree | |
Thesis Level | M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
Classification number | Cai01.11.16.M.Sc.2016.En.E |
100 0# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Enas Ezzat Mohammed Rateb |
245 10 - TITLE STATEMENT | |
Title | Effect of melatonin supplemented at the light or dark period on recovery of sciatic nerve injury in rats / |
Statement of responsibility, etc. | Enas Ezzat Mohammed Rateb ; Supervised Samah Elattar , Nashwa Eltablawy , Shimaa Nasr |
246 15 - VARYING FORM OF TITLE | |
Title proper/short title | تأثير إعطاء الميلاتونين فى فترات الضوء و الظلام على التعافى من إصابة العصب الوركى فى الفئران |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Cairo : |
Name of publisher, distributor, etc. | Enas Ezzat Mohammed Rateb , |
Date of publication, distribution, etc. | 2016 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 184 P. : |
Other physical details | charts , facsimiles ; |
Dimensions | 25cm |
502 ## - DISSERTATION NOTE | |
Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Histology |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Peripheral nerve injuries are commonly encountered in clinical practice due to several causes such as accidental trauma or surgery. All of these traumas can cause temporary or life-long disabilities that can subsequently lead to social or economic problems. Melatonin, the secretory product of the pineal gland exhibits an array of biological activities, including antioxidant and anti-inflammatory actions. The aim of the present study was to investigate the effect of melatonin on the recovery of sciatic nerve after injury with comparing its effect when it is given to the rats in the light or the dark period. Forty adult male wistar albino rats were randomly allocated into 4 groups, each one contains 10 rats: group 1 (control), group 2 (nerve injury), group 3 (nerve injury+melatonin given at light) and group 4 (nerve injury + melatonin given at dark). Nerve injury was initiated by clamping the sciatic nerves with a standard temporary aneurismal clip for 2 minutes for all groups except the control one. Sciatic functional index (SFI) was measured preoperatively for all groups and nerve injury was confirmed by measuring the sciatic functional index postoperatively. Melatonin was given as 50 mg/kg BW intraperitoneally daily for 6 weeks. Recovery of the function was analyzed by functional analysis [Sciatic function index], electrophysiological analysis [Nerve Conduction Velocity (NCV) and force of muscle contraction] and biochemical analysis by measuring - superoxide dismutase (SOD), Interleukin 1B (IL-1B), Nerve growth factor (NGF), and bcl-2 |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
Additional physical form available note | Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Apoptosis |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Melatonin |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Nerve injury |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Nashwa Eltablawy , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Samah Elattar , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Shimaa Nasr , |
Relator term | |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Nazla |
Reviser | Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Samia |
Reviser | Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Dewey Decimal Classification |
Koha item type | Thesis |
Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
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Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.16.M.Sc.2016.En.E | 01010110071113000 | 22.09.2023 | Thesis | ||
Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.16.M.Sc.2016.En.E | 01020110071113000 | 22.09.2023 | CD - Rom | 71113.CD |