Effect of certain compounds with possible anti-inflammatory activity on hepatic metabolizing enzymes in experimental animals / (Record no. 60074)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02701cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031657.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170304s2016 ua o f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.09.M.Sc.2016.Ma.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Maha Badr Mohamed Mohamed |
| 245 10 - TITLE STATEMENT | |
| Title | Effect of certain compounds with possible anti-inflammatory activity on hepatic metabolizing enzymes in experimental animals / |
| Statement of responsibility, etc. | Maha Badr Mohamed Mohamed ; Supervised Samira Saleh Mostafa , Sanaa Saber Botros |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثير مركبات معينة لها تأثير محتمل كمضاد للإلتهاب على إنزيمات الأيض الكبدية فى حيوانات التجارب |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Maha Badr Mohamed Mohamed , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 170 P. : |
| Other physical details | photographs ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Treatment of early stage of liver disease; hepatic inflammation can prevent progression to serious liver diseases. Unfortunately, the available conventional/synthetic pharmacotherapeutic options for liver diseases are inadequate and can have serious adverse effects. In the present study, hepatic inflammation was induced by IP injection of TAA in a dose of 100 mg / kg once/week for 4 weeks. Male albino rats (120-160g) were divided into 8 groups; group 1: normal control, group 2: TAA induced hepatic inflammation group, group 3-8 received TAA and treated with silymarin (positive control) (50 mg / kg), resveratrol (10 mg / kg), eugenol (10.7 mg / kg), LP (400 mg / kg), hesperidin (40 mg / kg) and HA (100 mg / kg), respectively. All treatments were given orally for 4 weeks. The tested compounds were examined with the regard to their effects on the following parameters: biochemical parameters including; liver function tests, lipid peroxidation and antioxidant markers and inflammatory cytokines markers. Histopathological and immunohistochemical examination including; caspase-3, nuclear factor kappa-B (NF-кB) and CYP2E1 were also examined. Treatment with resveratrol, eugenol, HA and silymarin caused normalization of ALT and AST values. LP and hesperidin decreased ALT and AST values but were unable to normalize the values |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Eugenol |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hepatic inflammation |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Resveratrol |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Samira Saleh Mostafa , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sanaa Saber Botros , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.09.M.Sc.2016.Ma.E | 01010110071163000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.09.M.Sc.2016.Ma.E | 01020110071163000 | 22.09.2023 | CD - Rom | 71163.CD |