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Histological study evaluating the regulatory effect of nitric oxide on experimentally injured skeletal muscle of male albino rat / (Record no. 60165)

MARC details
000 -LEADER
fixed length control field 02686cam a2200349 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250223031700.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 170308s2016 ua h f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.11.16.M.Sc.2016.Ma.H
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Mariam Ezzat Helmy
245 10 - TITLE STATEMENT
Title Histological study evaluating the regulatory effect of nitric oxide on experimentally injured skeletal muscle of male albino rat /
Statement of responsibility, etc. Mariam Ezzat Helmy ; Supervised Abeer Fouad Abdelmohsen , Abeer Fouad Abdelmohsen , Safinaz Salah Eldin Sayed
246 15 - VARYING FORM OF TITLE
Title proper/short title دراسة هستولوجية لتقييم التأثير التنظيمى لأكسيد النيتريك على العضلات الهيكلية بعد اصابتها تجريبياً فى ذكر الجرذ الأبيض
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Mariam Ezzat Helmy ,
Date of publication, distribution, etc. 2016
300 ## - PHYSICAL DESCRIPTION
Extent 175 P. :
Other physical details facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Histology
520 ## - SUMMARY, ETC.
Summary, etc. Nitric oxide (NO) has emerged as a regulator of myogenesis at several steps. This study was designed to evaluate the regulatory role of NO in skeletal muscle healing after crush injury in a rat model, using an inhibitor of NO synthesis NG-nitro-L-arginine-methyl ester (L-NAME) and a NO precursor (L-arginine). 60 rats were used in the study, 30 as control, and 30 were subjected to a crush injury to the right gastrocnemius muscle via mass falling from a height. Then 2 h. post trauma, 10 rats were injected with L-NAME, 10 rats with L-arginine and the remaining 10 rats did not receive any treatment. Histological and immuno-histochemical analysis (for iNOS, MMP-2 and PCNA) were done 24 h post trauma, also Masson{u2019}s trichrome stain to detect collagen 7 days after the trauma. Morphometric study and statistical analysis were done to measure the mean area percent of iNOS and MMP-2 immuno-reactivity, mean number of PCNA +ve cells/HPF, and mean area percent of collagen. It was found that the early changes occurring after the trauma and the degree of fibrosis were greatly dependent on NO, as with L-NAME injection the healing showed thick fibrous scar contrary to L-arginine, which resulted in a thin scar
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term L-NAME
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Nitric oxide
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Skeletal muscle
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Abeer Fouad Abdelmohsen ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Abeer Fouad Abdelmohsen ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Safinaz Salah Eldin Sayed ,
Relator term
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a>
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Samia
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.11.16.M.Sc.2016.Ma.H 01010110071250000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.11.16.M.Sc.2016.Ma.H 01020110071250000 22.09.2023 CD - Rom 71250.CD