Histological study evaluating the regulatory effect of nitric oxide on experimentally injured skeletal muscle of male albino rat / (Record no. 60165)
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000 -LEADER | |
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fixed length control field | 02686cam a2200349 a 4500 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | EG-GiCUC |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20250223031700.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 170308s2016 ua h f m 000 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | EG-GiCUC |
Language of cataloging | eng |
Transcribing agency | EG-GiCUC |
041 0# - LANGUAGE CODE | |
Language code of text/sound track or separate title | eng |
049 ## - LOCAL HOLDINGS (OCLC) | |
Holding library | Deposite |
097 ## - Thesis Degree | |
Thesis Level | M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
Classification number | Cai01.11.16.M.Sc.2016.Ma.H |
100 0# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Mariam Ezzat Helmy |
245 10 - TITLE STATEMENT | |
Title | Histological study evaluating the regulatory effect of nitric oxide on experimentally injured skeletal muscle of male albino rat / |
Statement of responsibility, etc. | Mariam Ezzat Helmy ; Supervised Abeer Fouad Abdelmohsen , Abeer Fouad Abdelmohsen , Safinaz Salah Eldin Sayed |
246 15 - VARYING FORM OF TITLE | |
Title proper/short title | دراسة هستولوجية لتقييم التأثير التنظيمى لأكسيد النيتريك على العضلات الهيكلية بعد اصابتها تجريبياً فى ذكر الجرذ الأبيض |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Cairo : |
Name of publisher, distributor, etc. | Mariam Ezzat Helmy , |
Date of publication, distribution, etc. | 2016 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 175 P. : |
Other physical details | facsimiles ; |
Dimensions | 25cm |
502 ## - DISSERTATION NOTE | |
Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Histology |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Nitric oxide (NO) has emerged as a regulator of myogenesis at several steps. This study was designed to evaluate the regulatory role of NO in skeletal muscle healing after crush injury in a rat model, using an inhibitor of NO synthesis NG-nitro-L-arginine-methyl ester (L-NAME) and a NO precursor (L-arginine). 60 rats were used in the study, 30 as control, and 30 were subjected to a crush injury to the right gastrocnemius muscle via mass falling from a height. Then 2 h. post trauma, 10 rats were injected with L-NAME, 10 rats with L-arginine and the remaining 10 rats did not receive any treatment. Histological and immuno-histochemical analysis (for iNOS, MMP-2 and PCNA) were done 24 h post trauma, also Masson{u2019}s trichrome stain to detect collagen 7 days after the trauma. Morphometric study and statistical analysis were done to measure the mean area percent of iNOS and MMP-2 immuno-reactivity, mean number of PCNA +ve cells/HPF, and mean area percent of collagen. It was found that the early changes occurring after the trauma and the degree of fibrosis were greatly dependent on NO, as with L-NAME injection the healing showed thick fibrous scar contrary to L-arginine, which resulted in a thin scar |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
Additional physical form available note | Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | L-NAME |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Nitric oxide |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Skeletal muscle |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Abeer Fouad Abdelmohsen , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Abeer Fouad Abdelmohsen , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Safinaz Salah Eldin Sayed , |
Relator term | |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Nazla |
Reviser | Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Samia |
Reviser | Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Dewey Decimal Classification |
Koha item type | Thesis |
Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
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Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.16.M.Sc.2016.Ma.H | 01010110071250000 | 22.09.2023 | Thesis | ||
Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.16.M.Sc.2016.Ma.H | 01020110071250000 | 22.09.2023 | CD - Rom | 71250.CD |