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Dexmedetomidine as an adjuvant to bupivacaine in transurethral resection of the prostate operations : (Record no. 60332)

MARC details
000 -LEADER
fixed length control field 03403cam a2200349 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250223031705.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 170319s2016 ua h f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level Ph.D
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.11.01.Ph.D.2016.Al.D
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Alaa Mahmoud Bahaa Eldin
245 10 - TITLE STATEMENT
Title Dexmedetomidine as an adjuvant to bupivacaine in transurethral resection of the prostate operations :
Remainder of title A dose response study /
Statement of responsibility, etc. Alaa Mahmoud Bahaa Eldin ; Supervised Ahmed Moneer Ahmed Shash , Hala Mostafa Goma , Atef Kamel Salama
246 15 - VARYING FORM OF TITLE
Title proper/short title تحديد آثار إضافة عقار الديكسمديتومدين إلى عقار البيوبيفاكان في عمليات تخدير إستئصال البروستاتا عبر الإحليل
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Alaa Mahmoud Bahaa Eldin ,
Date of publication, distribution, etc. 2016
300 ## - PHYSICAL DESCRIPTION
Extent 68 P. :
Other physical details facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anaesthesia
520 ## - SUMMARY, ETC.
Summary, etc. BACKGROUND Neuroaxial block is regarded as the preferred anaesthetic technique for TURP operations. Limited duration remains one of its downsides which led to introduction of adjuvants to local anaesthetics (LA). Dexmedetomidine is a highly selective Ü2 agonist and its Ü2/Ü1 selectivity is 8 times higher than clonidine. AIM In this study, we investigated the effect of adding dexmedetomidine to intrathecal bupivacaine on onset and duration of sensory and motor block in addition to sedation and hemodynamic changes. Our aim was to find the least effective dose with minimal or no side effects. STUDY DESIGN Randomised controlled double blind study. METHODS Forty five patients were randomly assigned into three groups. A control group (n=15): patients received 3ml (15mg) of hyperbaric bupivacaine (0.5%) + 0.5 ml normal saline, Dex 1.5 group(n=15): patients received 3ml (15 mg) of hyperbaric bupivacaine (0.5%) + 1.5æg dexmedetomidine and Dex 3 group(n=15): patients received 3 ml (15mg) of hyperbaric bupivacaine + 3æg dexmedetomidine. Sensory block reaching time to T10, highest sensory block level, sensory regression to S1, motor block onset time to bromage 3, motor block duration , sedation level and hemodynamics were all recorded. RESULTS Sensory and motor block duration were increased significantly between the groups in a dose-dependent manner (p<0.001), time to T10 dermatome was significantly shorter in dex containing groups (p<0.001), highest level of sensory block was significantly higher in group dex3 and dex1.5 rather than control group (p=0.011), however there was no statistically significant difference regarding complete onset of motor block. There was a statistically significant increase in the sedation level in a dose dependant manner (p<0.001) in relation to the control group. There were no statistically significant differences regarding demographic data, hemodynamics and adverse effects between the groups.
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Dexmedetomidine
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Neuroaxial block
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term TURP
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Ahmed Moneer Ahmed Shash ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Atef Kamel Salama ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Hala Mostafa Goma ,
Relator term
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a>
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Shaima
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.11.01.Ph.D.2016.Al.D 01010110071221000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.11.01.Ph.D.2016.Al.D 01020110071221000 22.09.2023 CD - Rom 71221.CD