Vascular endothelial growth factor as a marker of hepatocellular carcinoma / (Record no. 60690)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02858cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031717.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170419s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.18.M.Sc.2016.Sa.V |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Samaa Ayman Anwar Saiid |
| 245 10 - TITLE STATEMENT | |
| Title | Vascular endothelial growth factor as a marker of hepatocellular carcinoma / |
| Statement of responsibility, etc. | Samaa Ayman Anwar Saiid ; Supervised Rokaya Abdelaziz Mohammed , Nagwa Ramadan Ahmed , Hala Gabr Metwally |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | عامل نمو بطانة الأوعية الدموية كعلامة عن سرطان الكبد |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Samaa Ayman Anwar Saiid , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 208 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Vascular endothelial growth factor (VEGF) is a secreted homodimeric cytokine and a primary driving force for both physiological and pathological angiogenesis, and its overexpression has been found in hepatocellular carcinoma (HCC). Furthermore, the invasiveness of certain HCC lesions has recently been linked to high levels of VEGF. So, in our study we investigated the relation between serum VEGF levels and diagnosis of hepatocellular carcinoma as well as assessment of prognosis in HCC patients. Methods Patients with hepatocellular carcinoma and liver cirrhosis were prospectively enrolled. Blood samples drawn at the day of inclusion in the study were assessed for VEGF content by an enzyme-linked immunosorbent assay. VEGF levels were correlated with the presence as well as severity of hepatocellular carcinoma. The diagnostic value of VEGF was investigated by uni- and multivariate Cox regression analyses.results 90 patients were enrolled. Subjects with hepatocellular carcinoma (HCC) showed elevated serum levels of VEGF as compared to healthy subjects (1930.9+1060 pg/ml vs. 283+162.5 pg/ml, P=0.000). Patients with intra abdominal lymphnodes (P{u200A}={u200A}0.011) and more than one focal lesion (P{u200A}={u200A}0.044) had higher VEGF levels than patients without these findings. Low VEGF levels were a parameter independently associated with longer overall survival (sensitivity (83.3%) and specificity (81.7%) in prediction of HCC, with cut off value (872.5) |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hepatocellular carcinoma HCC |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Internal Medicine |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Vascular endothelial growth factor VEGF |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hala Gabr Metwally , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nagwa Ramadan Ahmed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rokaya Abdelaziz Mohammed , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shaima |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.18.M.Sc.2016.Sa.V | 01010110071522000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.18.M.Sc.2016.Sa.V | 01020110071522000 | 22.09.2023 | CD - Rom | 71522.CD |