Phytochemical and biological evaluation of zingiber officinale roscoe for the treatment of alzheimer's disease / (Record no. 60881)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02941cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031723.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170513s2016 ua o f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.07.M.Sc.2016.Ma.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Marwa Abualwafa Hussein Ebrahim |
| 245 10 - TITLE STATEMENT | |
| Title | Phytochemical and biological evaluation of zingiber officinale roscoe for the treatment of alzheimer's disease / |
| Statement of responsibility, etc. | Marwa Abu Alwafa Hussein Ebrahim ; Supervsied Magda Mohamed Fathy , Hanaa Hassan Eid , Ahmed Abdelfattah Hussein |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | التقييم الفيتوكيميائى و البيولوجى لنبات الزنجبيل فى علاج مرض الزهايمر |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Marwa Abualwafa Hussein Ebrahim , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 209 P. : |
| Other physical details | photographs ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Zingiber officinale commonly called ginger is being used in Arabian folk medicine for treatment of different diseases including improvement of memory impairment. The present study was designed to evaluate the role of ginger in treatment of alzheimer{u2019}s disease in-vitro and in-vivo. The phytochemical study was carried out using different chromatographic methods including GC/MS analysis of the volatile constituents of ginger essential oils (hydro-distilled and commercial) and phytochemical investigation of ginger methanolic extract using semi-preparative HPLC. Ginger methanolic extract and ginger essential oils (hydro-distilled and commercial) were tested for their antioxidant activity in-vitro against diphenylpicrylhydrazyl (DPPH) free radical and the inhibition activity against acetylcholinesterase enzyme (AChE) was tested using a multi-well plate Ellman{u2019}s assay. In addition, the methanolic extract and the commercial ginger oil were studied in-vivo using Alzheimer{u2019}s disease model induced in rats using oral AlCl3. Also, the antioxidant activity in-vitro of the isolated compounds from ginger methanolic extract was evaluated using DPPH free radical scavenging assay, superoxide radical scavenging activity assay, hydrogen peroxide scavenging activity assay and reducing power assay as well as the inhibition activity against acetylcholinesterase enzyme (AChE) was evaluated using a multi-well plate Ellman{u2019}s assay. Results showed that both essential oils participated in 25 common volatile components |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Alzheimer{u2019}s disease |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Ginger |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Zingiber officinale |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Abdelfattah Hussein , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hanaa Hassan Eid , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Magda Mohamed Fathy , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.07.M.Sc.2016.Ma.P | 01010110071662000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.07.M.Sc.2016.Ma.P | 01020110071662000 | 22.09.2023 | CD - Rom | 71662.CD |