Analytical study on some drugs used in treatment of CNS disorders / (Record no. 61191)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02849cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031732.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170613s2016 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.03.M.Sc.2016.Yo.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Yosra Zakaria Sewilam |
| 245 10 - TITLE STATEMENT | |
| Title | Analytical study on some drugs used in treatment of CNS disorders / |
| Statement of responsibility, etc. | Yosra Zakaria Sewilam ; Supervised Soheir Abdelfattah Weshahy , Nagiba Yehia Hassan , Maha Abdelmonem Hegazy |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة تحليلية على بعض الأدوية المستخدمة فى علاج أمراض الجهاز العصبى المركزى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Yosra Zakaria Sewilam , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 263 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Multicomponent pharmaceutical formulations have gained a lot of importance due to greater patient acceptance as a result of reduced pill burden, increased potency and multiple actions. Accordingly, estimation of drugs in combination therapy simultaneously is an important part in the field of pharmacy as it saves time of separation and yields accurate and precise results. As most pharmaceutical compounds are subjected to degradation which results in change in their activity, stability-indicating assay methods were developed for the selective determination of the intact drug in the presence of its degradation product. In this study different analytical techniques were applied for analysis of some CNS acting drugs either in combination or in the presence of their degradates. The chosen drugs are namely entacapone, bromazepam, levodopa and carbidopa. The aim of the work was to develop accurate, economic and selective methods for the analysis of the chosen drugs simultaneously in combination dosage forms and without interference from their degradates and to investigate the stability of the studied drugs according to ICH guidelines by exposing it to different stress conditions followed by developing stability indicating assay methods for the analysis of the active ingredient in presence of its degradation product. The proposed methods were simple, accurate, and reproducible, which would be feasible and sensitive for the determination of the studied drugs and were validated according to ICH-guideline |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Bromazepam |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Entacapone |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Levodopa |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maha Abdelmonem Hegazy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nagiba Yehia Hassan , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Soheir Abdelfattah Weshahy , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.03.M.Sc.2016.Yo.A | 01010110071829000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.03.M.Sc.2016.Yo.A | 01020110071829000 | 22.09.2023 | CD - Rom | 71829.CD |