Biopharmaceutical study on selected improved carvedilol formulae in a certain dosage form / (Record no. 61216)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02298cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031732.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170614s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.08.M.Sc.2016.Do.B |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Doaa Mahmoud Abdelhamid Garhy |
| 245 10 - TITLE STATEMENT | |
| Title | Biopharmaceutical study on selected improved carvedilol formulae in a certain dosage form / |
| Statement of responsibility, etc. | Doaa Mahmoud Abdelhamid Garhy ;supervised Mahmoud M. Ghorab , Howaida K. Ibrahim , Soha A. Ismail |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة بيوصيدلية لأشكال معدلة ومختارة من عقار الكارفيديلول فى شكل معين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Doaa Mahmoud Abdelhamid Garhy , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 182 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Novel drug delivery dosage forms can provide improved benefits as enhancement in bioavailability, reduction of adverse effects and economic benefits. Elderly people may experience deterioration in their physiological and physical abilities which may lead to encountering difficulties in taking conventional dosage forms due to dysphagia. Carvedilol is Ü1/ non-cardioselective Ý-blocker that is used in the treatment of hypertension and many cardiovascular disorders. It is insoluble in water, intestinal fluids and gastric fluids that undergoes extensive first pass effect and has oral bioavailability of only 25-35%. Therefore, the aim of this thesis is to enhance the bioavailability through preparation of carvedilol nanoparticles to enhance dissolution and so absorption. Also, incorporation of the prepared nanoparticles in a gel form for buccal application to bypass the first pass effect and enhance the bioavailability |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Carvedilol formulae |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Certain dosage form |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Pharmaceutics |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Howaida K. Ibrahim , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mahmoud M. Ghorab , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Soha A. Ismail , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.08.M.Sc.2016.Do.B | 01010110071861000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.08.M.Sc.2016.Do.B | 01020110071861000 | 22.09.2023 | CD - Rom | 71861 CD |