Evaluation of some bioactive compounds as anti-virulent agents to acinetobacter baumannii / (Record no. 61346)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03028cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031737.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170619s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.06.M.Sc.2016.Mo.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mona Hassan Mahmoud |
| 245 10 - TITLE STATEMENT | |
| Title | Evaluation of some bioactive compounds as anti-virulent agents to acinetobacter baumannii / |
| Statement of responsibility, etc. | Mona Hassan Mahmoud ; supervisied Magdy Aly Amin , Aly Fahmy Mohamed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم بعض المركبات الفعالة بيولوجيا كمضادات للضراوة فى بكتيريا الأسينيتوبكتر بومنياى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mona Hassan Mahmoud , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 127 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 30.cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Acinetobacter baumannii is a remarkable hospital pathogen, notably due to the dissemination of highly multidrug resistant isolates and the treatment options for infections caused by multi-drug resistant (MDR) A. baumannii strains constitute a strong challenge. The virulence factors of this organism such as biofilm formation, bacterial adherence, and bacterial invasion and efflux pumps help the bacterium to survive in diverse environmental conditions and facilitate the development of an infection. Antiseptics are frequently used for the management of MDR pathogens in hospitals and their consistent use in hospitals has elevated concerns about its resistance. The aim of this study was to determine the effect of subminimum inhibitory concentrations (sub-MICs) of selected antimicrobial agents (amikacin, imipenem, benzalkonium chloride (BZC), and chlorhexidine) and natural product (garlic) on biofilm formation, bacterial adherence and invasion and the emergence of resistance among A. baumannii clinical isolates. Susceptibility profiles of 50 non-repetitive A. baumannii isolated from admitted patients in two tertiary care hospitals in Cairo, Egypt to eight different antibiotics were investigated. MIC of various antibiotics, antiseptics and garlic were determined by the broth microdilution method. Quantification of biofilm formation was carried out using a microtiter plate assay. The ability of test compounds to affect the bacterial adherence and invasion was investigated using Type II pneumocyte cell line A549 derived from a human lung carcinoma and the bacterial cells count was determined in each well using flow cytometer. Screening for the presence of antiseptic resistance gene qacA/B was done using PCR |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Clasp |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Retention |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Thermoplastic resin |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Aly Fahmy Mohamed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Magdy Aly Amin , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.06.M.Sc.2016.Mo.E | 01010110072007000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.06.M.Sc.2016.Mo.E | 01020110072007000 | 22.09.2023 | CD - Rom | 72007.CD |