Assessment of vascular endothelial growth Factor (VEGF) as a new non-invasive marker for early prediction of esophageal varices in chronic liver disease patients / (Record no. 61480)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03284cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031741.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170708s2016 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.18.M.Sc.2016.Sa.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sarah Ahmad Mohamad Elmorsy |
| 245 10 - TITLE STATEMENT | |
| Title | Assessment of vascular endothelial growth Factor (VEGF) as a new non-invasive marker for early prediction of esophageal varices in chronic liver disease patients / |
| Statement of responsibility, etc. | Sarah Ahmad Mohamad Elmorsy ; Supervised Yasser Bakr Mohamed , Ula Mabid Aljarhi , Mona Mohsen Abdelsalam |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم عامل نموالنسيج البطانى للأوعية الدموية كعلامة جديدة للتنبؤ المبكر بدوالى المرىء فى المرضى الذين يعانون من أمراض الكبد المزمنة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Sarah Ahmad Mohamad Elmorsy , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 151 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: The gold standard screening technique for presence of esophageal varices and its risk for bleeding is upper GI endoscopy. The development of a non-invasive method for early prediction of esophageal varices and its risk of bleeding would identify high-risk patients with lesser need for expensive, risky and invasive endoscopy. VEGF is known as an important angiogenic factor and has a crucial role in portal hypertension and collateral vessels formation. Objectives: Assessment of urinary VEGF level in cirrhotic patients as a predictor of presence and severity of esophageal varices. Methods: 42 cirrhotic patients were randomly selected and classified into 2 groups according to the presence or absence of variceal bleeding. VEGF was measured in urine of both groups and compared to 42 healthy controls. VEGF level was corrected against urinary creatinine. Platelet count, liver function tests, abdominal ultrasonography and upper GI endoscopy were done to all patients. The association between urinary VEGF and all previous parameters as well as with clinical data was sought. Results: Significantly lower levels of urinary VEGF were detected in cirrhotic patients with esophageal varices than those without, and both groups were lower than that of controls. By multivariable logistic regression, low VEGF, low platelet count and splenomegaly were found to be independent predictors of both the presence of large esophageal varices, and variceal bleeding. Receiver operating characteristic (ROC) curve analysis showed that platelet count{u2264} 166.3x10 ³/ æL, and corrected VEGF{u2264}59.12 pg/mg were predictive of large esophageal varices with 93.1%, 86.2% sensitivity and 74.5%, 58.2% specificity respectively |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Esophageal varices |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Liver cirrhosis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Portal hypertension |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mona Mohsen Abdelsalam , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ula Mabid Aljarhi , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yasser Bakr Mohamed , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.18.M.Sc.2016.Sa.A | 01010110072062000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.18.M.Sc.2016.Sa.A | 01020110072062000 | 22.09.2023 | CD - Rom | 72062.CD |