Novel non-invasive biomarkers in colorectal cancer : (Record no. 61504)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02758cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031742.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170709s2016 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.35.Ph.D.2016.Pa.N |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Pakinam Mohamed Samir Elshanawany |
| 245 10 - TITLE STATEMENT | |
| Title | Novel non-invasive biomarkers in colorectal cancer : |
| Remainder of title | A case-control study in Kasr Alainy hospital / |
| Statement of responsibility, etc. | Pakinam M. Samir Elshanawany ; Supervised Nagwa Eid Saad , Mahmoud Hassan Elguibaly , Mona Salah Hamdy |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | مؤشرات حيويه جديده غير تداخليه فى سرطان القولون و المستقيم : |
| Remainder of title | دراسه حالات افتراضيه مقترنه بحالات ضابطه بالقصر العينى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Pakinam Mohamed Samir Elshanawany , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 150 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Family Medicine |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Colorectal cancer (CRC) is the third most common cancer worldwide after lung and breast cancers. The problem of early detection of CRC in Egypt is severe, as the cost of colonoscopy often exceeds a person's yearly salary, and there are not enough trained personnel or adequate centres to perform it. The discovery of microRNAs, has led to active research focusing on their role in the diagnosis of CRC. ObjectiIves: The objective of this study is to evaluate the specificity and sensitivity of serum biomarkers (micro-RNAs), miR-1246, miR-23a, and miR-451 in patients with CRC. Methodology: The present study is a case-control study. Microarray analysis of miRNA-1246, -23a, and -451 in serum samples from 37 primary CRC patients and 30 controls were performed. RESULTS: The serum levels of miRNA-1246 (p< 0.000) and miRNA-451 (p=0.014) were significantly higher in primary CRC patients than incontrols. The area under the ROC curve for miRNA-1246 was 0.924, with sensitivity (100%) and specificity (80%). The area under the ROC curve for MiR-23a was 0.67027, with sensitivity (70.3%) and specificity (70%). The area under the ROC curve for miRNA-451 was 0.757, with sensitivity (73%) and specificity (80%). Conclusion: MiRNA-1246 appears to be a promising non-invasive biomarker in CRC |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Micro-RNAs |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Non-invasive diagnosis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Serum biomarkers |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mahmoud Hassan Elguibaly , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mona Salah Hamdy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nagwa Eid Saad , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.35.Ph.D.2016.Pa.N | 01010110072071000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.35.Ph.D.2016.Pa.N | 01020110072071000 | 22.09.2023 | CD - Rom | 72071.CD |