MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03007cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
170718s2016 ua o f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.08.07.M.Sc.2016.Sh.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Sherif Ahmed Muhammed Ahmed Hamdy |
| 245 12 - TITLE STATEMENT |
|---|
| Title |
A pharmacognostical study of hydrocotyle umbellata L. (Fam. Araliaceae) , grown in Egypt / |
| Statement of responsibility, etc. |
Sherif Ahmed Muhammed Ahmed Hamdy ; Supervsied Elsayed A. Aboutabl , Shadia M. Azzam , Hala M. Elhefnawy |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
دراسة عقاقيرية لنبات الهيدروكوتيل امبللاتا عائلة (الارالياسى) الذى ينمو فى مصر |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Sherif Ahmed Muhammed Ahmed Hamdy , |
| Date of publication, distribution, etc. |
2016 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
286 P. : |
| Other physical details |
photographs ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Genetic fingerprinting and botanical profiling including macro-and micro-morphological studies of the different organs of hydrocotyle umbellata L. were done for identification and authentication of the plant. The biological study included anti-oxidant, anticholinestrase, anti-inflammatory and antihyperglycemic activities. The N-hexane and defatted ethanolic extract (DEE) of the aerial parts were found to be safe and non-toxic up to 2g/Kg of body weight. The anti-oxidant and anticholinestrase activities were examined by in-vitro assays (DPPH scavenging and acetyl cholinesterase inhibition models, respectively). The N-hexane extract showed significant anti-acetylcholinestrase activity, while the DEE exhibited both DPPH scavenging and cholinesterase inhibition activities with its ethyl acetate fraction being the most active one. The anti-inflammatory and antihyperglycemic activities were examined by in-vivo assays (STZ-induced diabetic rats model and carrageenan induced paw odema model, respectively). The DEE exhibited both antihyperglycemic and anti-inflammatory activities, while n-hexane extract only showed anti-inflammatory activity. Preliminary phytochemical screening, proximate analysis, investigation of the lipoidal content of the aerial parts in addition to investigation of the volatile oil of the leaves and flowers, qualitative determination of the secondary metabolite composition of both leaves and flowers using UPLC-MS with major detected peaks corresponding to the isolated compounds, and phytochemical investigation of the biologically active fractions (n-hexane and ethyl acetate fractions) using different chromatographic techniques were done |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Biological study |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Botanical profiling |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Hydrocotyle umbellata L. |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Elsayed Ali Aboutabl , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Hala Mohamed Elhefnawy , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Shadia Mazloum Azzam , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Samia |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
