Optimization of valproic acid-loaded lipid nanocapsules for potential nose-to-brain targeting / (Record no. 61699)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02051cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031748.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170729s2014 ua dho f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Gift |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.34.M.Sc.2014.Ma.O |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Marco Kerolos Abdallah Kerolos Rizk |
| 245 10 - TITLE STATEMENT | |
| Title | Optimization of valproic acid-loaded lipid nanocapsules for potential nose-to-brain targeting / |
| Statement of responsibility, etc. | Marco Kerolos Abdallah Kerolos Rizk ; Supervsied Nagia Nagib Afifi , Rania Mohammed Hathout , Reham Mahmoud Abdelkader |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تحسين صياغات كبسولات نانونية دهنية محملة بعقار حمض الفالبوريك لرفع احتمالية تهديف العقار للمخ عن طريق الأنف |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Marco Kerolos Abdallah Kerolos Rizk , |
| Date of publication, distribution, etc. | 2014 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 77 Leaves : |
| Other physical details | charts , facsimiles , photographs ; |
| Dimensions | 30cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Technology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Valproic acid ias an important drug for its role in the treatment of epilepay as well as other CNS disorders. Unfortunately, it suffers from two main problems, its poor brain bioavailability owing to ecessive binding to plasma proteins and its efflux outside the brain by the action of P-gp pumps. Accordingly, higher doses are needed resulting in serious side effects such as liver toxicity. Morcover, the conventional dosage forms of the drug which are available now in the market offer less than 10% brain bioavailability |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Lipid nanocapsules |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Potential nose-to-brain targeting |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Valproic acid-loaded |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nagia Nagib Afifi , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rania Mohammed Hathout , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Reham Mahmoud Abdelkader , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type |
|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الثقاقات الاجنبية - الدور الثالث | 11.02.2024 | Cai01.34.M.Sc.2014.Ma.O | 01010110072278000 | 05.07.2024 | Thesis |