Immunohistochemical expression of epcam in mucoepidermoid carcinoma and solid variant of adenoid cystic carcinoma compared to normal salivary gland tissues : (Record no. 62184)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03227cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031802.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170905s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.09.13.M.Sc.2016.No.I |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Noura Mohamed Kamal Eldin Mohamed Aly |
| 245 10 - TITLE STATEMENT | |
| Title | Immunohistochemical expression of epcam in mucoepidermoid carcinoma and solid variant of adenoid cystic carcinoma compared to normal salivary gland tissues : |
| Remainder of title | Observational study / |
| Statement of responsibility, etc. | Noura Mohamed Kamal Eldin Mohamed Aly ; Supervised Hend Mohammad Waguih Mahmoud Salem , Heba Mahmoud Dahmoush |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | في سرطان مخاطية بشروية و النوع الصلب من سرطان غدانية كيسية مقارنة مع أنسجة الغدة اللعابية الطبيعية EpCAM تعبيرمناعي : |
| Remainder of title | دراسة وصفية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Noura Mohamed Kamal Eldin Mohamed Aly , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 127 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Surgery |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Evaluate the immunohistochemical expression of EpCAM in different grades of MEC and solid variant of adenoid cystic carcinoma (solid AdCC) in comparison with the normal salivary glands, to ascertain the possible prognostic significance and propose EpCAM targeted therapy as a possible treatment approach for patients with salivary gland tumors overexpressing this cell surface marker.Material and Methods: A total of 60 archival paraffin embedded specimens (12 normal salivary gland tissue, 36 MEC and 12 Solid AdCC) were collected and EpCAM expression was evaluated by immunohistochemistry. The total immunoscore (TIS) was evaluated, which represented the product of the proportion score (PS) and the intensity score (IS). The term {u2018}EpCAM overexpression{u2019} was given for tissues showing a total immunostaining score >4. Results: A highly significant difference was detected between TIS percent values in control, different grades of MEC and solid AdCC. In MEC, EpCAM expression increased in HG-MEC compared to IMG-MEC and LG-MEC (Pearson's chi square test, p < 0.01), but no significant difference was observed between LG-MEC and IMG-MEC (Pearson's chi square test, P> 0.05). Solid AdCC showed the highest TIS percent values in relation to different grades of MEC. HG-MEC and solid AdCC were found to be the highest EpCAM expressors (TIS>4). Although, lack of EpCAM expression was detected in 2 cases (16.7%) of HG-MEC and one case (8.3%) of solid AdCC. Conclusion: EpCAM was frequently detected in MEC and solid AdCC making these tumours potential targets for anti-EpCAM therapies |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | EpCAM |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Mucoepidermoid carcinoma and solid adenoid cystic carcinoma |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Oral and Maxillofacial Surgery |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Heba Mahmoud Dahmoush , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hend Mohammad Waguih Mahmoud Salem , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Enas |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.09.13.M.Sc.2016.No.I | 01010110072513000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.09.13.M.Sc.2016.No.I | 01020110072513000 | 22.09.2023 | CD - Rom | 72513.CD |