MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02657cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
170907s2016 ua do f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.10.05.M.Sc.2016.Ah.T |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ahmed Mohamed Mohamed Abdellah |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Therapeutic effect of bone marrow derived mesenchymal stem cells in rats : |
| Remainder of title |
Experimental clinico-pathological and pathological study / |
| Statement of responsibility, etc. |
Ahmed Mohamed Mohamed Abdellah ; Supervised Mohamed Ibrahim Dessouky , Nashwa Adel Abu-Aita , Hanaa Ahmed Amer |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
التأثير العلاجى للخلايا الجزعية الوسيطه المستخلصه من نخاع العظام على التليف الكبدى فى الفئران : |
| Remainder of title |
دراسة تجريبية باثولوجية إكلينيكية و باثولوجية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Ahmed Mohamed Mohamed Abdellah , |
| Date of publication, distribution, etc. |
2016 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
163 P. : |
| Other physical details |
charts , photographs ; |
| Dimensions |
30cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Clinical Pathology |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Stem cells' therapy provides a novel therapeutic strategy for treatment of liver fibrosis and cirrhosis, and can be considered as an alternative to liver transplantation. The concept of the present study was to evaluate the therapeutic effect of bone marrow derived mesenchymal stem cells in carbon tetrachloride induced liver fibrosis in rats. S/C administration of carbon tetrachloride to Wistar rats for six weeks at a dose of 0.2 ml/100 gm body weight altered hematological and biochemical parameters. It induced significant leukocytosis, elevated the activities of hepatic enzymes (AST, ALT and ALP), increased serum bilirubin concentration and induced significant hypoproteinemia and hypoalbumemia. Moreover, it increased the percentage of fibrous tissue in liver parenchyma. Administration of bone marrow derived mesenchymal stem cells at a dose of 3{u00D7}106 cells per rat alleviated alterations in the previously mentioned hematological, biochemical and histopathological parameters. The obtained results suggested that bone marrow derived mesenchymal stem cells can be a potent cellular therapy for liver fibrosis |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Bone marrow derived mesenchymal stem cells |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Carbon tetrachloride |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Liver fibrosis |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Hanaa Ahmed Amer , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohamed Ibrahim Dessouky , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Nashwa Adel Abuaita , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Enas |
| Reviser |
Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
