Possible memory protective role of simvastatin and insulin in a rat model of diabetes mellitus and dementia / (Record no. 62244)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03049cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031803.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170910s2017 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.29.M.Sc.2017.Ve.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Veronia Fawzy Fahim |
| 245 10 - TITLE STATEMENT | |
| Title | Possible memory protective role of simvastatin and insulin in a rat model of diabetes mellitus and dementia / |
| Statement of responsibility, etc. | Veronia Fawzy Fahim ; Supervised Amani Nabil Shafik , Magdy Ishak Attallah , Walaa Wadie Ibrahim |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | الدور الوقائى المحتمل لسيمفاستاتين و الإنسولين على الذاكرة فى نموذج البوال السكرى و الخرف التجريبى المحدث فى الجرذان |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Veronia Fawzy Fahim , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 161 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pharmacology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Introduction: This study is an experimental study to investigate the possible memory protective role of insulin and simvastatin (at doses of 10 and 20 mg/kg/day) in a rat model of diabetes mellitus and dementia. Materials and methods: 100 healthy adult female albino rats weighing 200-250 gm were used and divided into two main groups. Group 1: control normoglycemic rats including 4 subgroups (10 rats/ each): Group 1a Untreated rats were left to the end of the experiment, Group 1b rats received volume of 0.5 ml (0.1 M) sodium citrate buffer single intraperitoneal injection, Group 1c rats received simvastatin 10 mg/kg/day by oral gavage and Group 1d rats received simvastatin 20 mg/kg/day by oral gavage. Group 2 Diabetic animals where DM was induced by a single intraperitoneal injection of streptozotocin (STZ) 60 mg/kg body weight. This group included 6 subgroups: Group 2a untreated rats, Group 2b Insulin treated rats, Group 2c Simvastatin treated rats in a dose of 10 mg/kg/day orally, Group 2d Simvastatin treated rats in a dose of 20 mg/kg/day orally, Group 2e Insulin+simvastatin (10 mg/kg/day) treated rats, Group 2f Insulin+simvastatin (20 mg/kg/day) treated rats. Treatment started after rise of blood glucose and continued for 6 weeks. To detect behavioral changes (long and short memory whether spatial or non-spatial), Morris water maze test was done 4 times; before induction of DM and every 2 weeks and Y maze test was held after 6 weeks at the end of the experiment. Serum samples were obtained from the retro-orbital sinus for measuring glucose, cholesterol and insulin levels |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Memory deficits |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Morris water maze test |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Simvastatin |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amani Nabil Shafik , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Magdy Ishak Attallah , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Walaa Wadie Ibrahim , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.29.M.Sc.2017.Ve.P | 01010110072606000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.29.M.Sc.2017.Ve.P | 01020110072606000 | 22.09.2023 | CD - Rom | 72606.CD |