Studies on the effect of antioxidant (Vitamin E & Selenium) on some organs of albino Rats exposed to lead acetate / (Record no. 62268)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03335cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031804.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170911s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.10.08.Ph.D.2016.Ya.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Yasmine Hamdy Ahmed Awad-Allah |
| 245 10 - TITLE STATEMENT | |
| Title | Studies on the effect of antioxidant (Vitamin E & Selenium) on some organs of albino Rats exposed to lead acetate / |
| Statement of responsibility, etc. | Yasmine Hamdy Ahmed Awad-Allah ; Supervised Nagwan Mohamed Youssef , Gehad Abdelfattah Hassan , Hany A. Elhabback |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسات على تأثير مضادات الأكسدة (فيتامين هـ والسيلينيوم) علي بعض الأعضاء فى الفئران البيضاء المعرضة لخلات الرصاص |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Yasmine Hamdy Ahmed Awad-Allah , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 186 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Histology and Cytology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This study conducted on mature fourty albino rats of both sexes to evaluate the effect of vitamin E and Selenium role to ameliorate histological alterations induced by lead toxicity. Rats divideded into 4 groups. Group I: control given distilled water. Group II: exposed group administrated orally sublethal dose of (10mg/kg bwt) lead acetate trihydrate, Group III: administrated vitamin E and selenium (1ml/liter D.W) plus lead acetate trihydrate and Group IV: administrated vitamin E and selenium in drinking water. The structural changes in liver, kidney and spinal cord were investigated by histological, histomorphometrical, histochemical, transmission electron microscopy, biochemical assay of liver enzymes, albumin, renal urea, creatinine and immunohistochemical examination. The results of lead exposed rats showed apparently dilated central vein and blood sinusoids in hepatic tissue, dilated renal glomerular capillaries that filled with blood. Interrupted myelin sheath in white matter nerve fibers of spinal cord. Decreased concentration of (GSH) in three organs compared to control. Significant elevation of liver enzymes, urea, creatinine and reduction in albumin level in serum. positive COX2 immunoreactivity in cytoplasm of most hepatocytes. Weak GFAP expression in astrocytes. On the other hand in vitamin E and Selenium plus lead acetate administrated group revealed narrow hepatic sinusoids and renal glomerular capillaries appeared less filled with blood. The myelin sheath appeared normal. Elevation of GSH concentration in three organs. Significant reduction in liver enzymes, urea, creatinine and elevation of albumin level. Positive COX2 reaction in cytoplasm of some hepatocytes. Moderate GFAP expression in astrocyte. Therefore vitamin E and Selenium had a protective role against lead acetate effect |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Histology |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Immunohistochemistry |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Lead acetate |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gehad Abdelfattah Hassan , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hany Ahmed Elhabback , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nagwan Mohamed Youssef , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Enas |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.10.08.Ph.D.2016.Ya.S | 01010110072522000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.10.08.Ph.D.2016.Ya.S | 01020110072522000 | 22.09.2023 | CD - Rom | 72522.CD |