Evaluation of cognitive functions and Diffusion tensor imaging mri in patients With juvenile myoclonic epilepsy / (Record no. 62301)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03306cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031805.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170912s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.21.Ph.D.2016.Lo.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Lobna Ahmed Talaat Elghoneimy |
| 245 10 - TITLE STATEMENT | |
| Title | Evaluation of cognitive functions and Diffusion tensor imaging mri in patients With juvenile myoclonic epilepsy / |
| Statement of responsibility, etc. | Lobna Ahmed Talaat Elghoneimy ; Supervised Iman Elbanhawy , Nermeen Adel , Kamel Hamouda |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم مرضي صرع الرجفة الفتياني للوظائف المعرفية بالرنين المغناطيسي موتر الانتشار |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Lobna Ahmed Talaat Elghoneimy , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 174 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine- Department of Neuropsychiatry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | as been reported with significant impairment on tests of frontal functioning. The JME group had poor performance on tests requiring concept formation and mental flexibility, and had difficulties in focusing attention and inhibiting habitual response sets. Cognitive correlates of JME have received little attention despite the extensive studies of cognition in other types of epilepsy. Aim of work: Study the cognitive performance in patients with JME. Determine the relation between neuroanatomical/neurophysiological abnormalities, and epileptic clinical characteristics with the cognitive performance in patients with JME. Methods: Fifty patients with JME and a sample of healthy controls were assessed using a series of neuropsychological tests as well as diffusion tensor MRI (DTI) and tractography. DTI measures assessed fractional anisotropy (FA) within a white matter skeleton. Results: Cognitive testing indicated subtle dysfunction in verbal learning and memory, phonemic and semantic fluency, attention, speed and mental flexibility. Using white matter diffusion MRI data, we found reductions in FA in underlying white matter of the left anterior corpus callosum, right supplementary motor area and left anterior cingulate. Reduced FA in the left anterior corpus callosum predicted uncontrolled generalized tonic-clonic convulsions (GTCs). As well as reduced FA in the left anterior corpus callosum and left anterior cingulate predicted uncontrolled myoclonus. Conclusion: Patients with JME had lower cognitive performance in verbal learning and memory, attention, speed and mental flexibility, which was associated with white matter cortical/subcortical microstuctural alterations. Uncontrolled GTCs is an important predictor of lower cognitive performance between JME patients. As well as a cortical/subcortical alterations being a predicting factor for uncontrolled GTCs and Myoclonus |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cognitive assessment |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Fractional anisotropy |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Juvenile myoclonic epilepsy |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Iman Elbanhawy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kamel Hamouda , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nermeen Adel , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.21.Ph.D.2016.Lo.E | 01010110072455000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.21.Ph.D.2016.Lo.E | 01020110072455000 | 22.09.2023 | CD - Rom | 72455.CD |