Assessment of CMV-specific CD8⁺T lymphocytes after stem cell transplantation / (Record no. 62316)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03076cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031806.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170916s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.07.Ph.D.2016.Sa.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Said Fathy Hotar |
| 245 10 - TITLE STATEMENT | |
| Title | Assessment of CMV-specific CD8⁺T lymphocytes after stem cell transplantation / |
| Statement of responsibility, etc. | Said F. Hotar ; Supervised Ahmed Ali Shams Eldin , Nermeen Ahmed Eldesoukey , Neveen M. Baha Eldin Fouad |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | قياس الخلايا الليمفاوية من النوع الايجابى ل سى دى 8 و المضاده للفيروس المضخم للخلايا (سى ام {uئآ٦آ}) فى مرضى زراعة الخلايا الجزعية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Said Fathy Hotar , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 155 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Hematopoietic stem cell transplant (SCT) is one of the most important lines of treatment of hematological and non hematological diseases which may be allogeneic, autologous using bone marrow, peripheral blood or placental blood. Human cytomegalovirus (CMV) infects 60-90% of individuals worldwide and remains latent in the infected host, CMV infection is an important cause of morbidity and mortality in immunosuppressed hematopoietic stem cell transplant (SCT) recipients. CMV-specific CD8+cytotoxic T lymphocytes play a critical role in suppressing CMV reactivation. The antigen-specific T lymphocytes may be enumerated without the requirement of in vitro stimulation by flowcytometry using major histocompatibility complex (MHC) tetramers. MHC tetramers are complexes between HLA class I or class II molecules and specific antigenic peptides conjugated to fluorochromes, These complexes bind to a distinct set of T-cell receptors on a subset of CD8-T cells. The iTAg MHC Tetramers show a greatly diminished binding to the general population of CD8 cells allowing for rapid and sensitive quantitative measurement of an individual patient's T cell response to a specific virus, So evaluation of MHC Tetramer measurement of this response and correlating it with recovery against CMV is expected to be of great help of planning antiviral therapy regimen. Post transplantation immunodeficiency needs immunotherapy or immunization strategies to control the recovery of T-cell responses against viral antigens, as well as those used to manage graft-versus-host disease and infection following transplantation |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Bone marrow transplantation |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | CMV |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Flowcytometry |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Ali Shams Eldin , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nermeen Ahmed Eldesoukey , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Neveen Mohamed Baha Eldin Fouad , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.07.Ph.D.2016.Sa.A | 01010110072634000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.07.Ph.D.2016.Sa.A | 01020110072634000 | 22.09.2023 | CD - Rom | 72634.CD |