Association analysis for big data related to rheumatoid arthritis based on haplotype block partitioning and single nucleotide polymorphisms / (Record no. 62390)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02971cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031808.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170918s2017 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.13.03.Ph.D.2017.Mo.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Nagy Saad Mohamed Elziftawy |
| 245 10 - TITLE STATEMENT | |
| Title | Association analysis for big data related to rheumatoid arthritis based on haplotype block partitioning and single nucleotide polymorphisms / |
| Statement of responsibility, etc. | Mohamed Nagy Saad Mohamed Elziftawy , supervised Ayman M. Eldeib , Olfat G. Shaker , Mai S. Mabrouk |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تحليل المزاملة لبيانات ضخمة مرتبطة بداء ألتهاب المفاصل الروماتويدي بناء على تقسيم كتلة النمط الفرداني وتعدد أشكال النوتيدات الواحدة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mohamed Nagy Saad Mohamed Elziftawy , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 101 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 30cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Engineering - Department of Systems and Biomedical Engineering |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Genetics of autoimmune diseases represent a growing domain with surpassing biomarker results with rapid progress. Rheumatoid arthritis (RA) is an autoimmune disease which has a significant socio-economic impact. The exact cause of RA is unknown, but it is thought to have both a genetic and an environmental bases. This thesis is concerned with the methods of identifying the genetic biomarkers of RA. Most of the researchers in the field of identifying RA biomarkers use single nucleotide polymorphism (SNP) approaches to express the significance of their results. Although, haplotype block methods are expected to play a complementary role in the future of that field. The used datasets belong to Egyptian population (185 individuals, 8 SNPs) and North American population (2,062 individuals, 545,080 SNPs). Our goal in this thesis differs according to the studied dataset. For the Egyptian dataset, the goal is the detection of the significant SNPs that are associated with RA disease. The individual SNP approaches that were used with the Egyptian population are multiplicative, co-dominant, dominant, and recessive approaches. The haplotype methods couldn{u2019}t be applied on the Egyptian dataset because of the small number of the studied SNPs. The associations between the eight SNPs and RA susceptibility and severity were detected using the four applied individual SNP approaches |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Genetic Association Study |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Haplotype Block |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Linkage Disequilibrium |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ayman M. Eldeib , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mai S. Mabrouk , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Olfat G. Shaker , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.13.03.Ph.D.2017.Mo.A | 01010110072473000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.13.03.Ph.D.2017.Mo.A | 01020110072473000 | 22.09.2023 | CD - Rom | 72473.CD |